Evidence map›Paper›PMID 39824852›Full record

ArticleNPJ biofilms and microbiomes2025

Streptococcus abundance and oral site tropism in humans and non-human primates reflects host and lifestyle differences.

Irina M Velsko, Christina Warinner

Abstract read
In one paragraph

Article in NPJ biofilms and microbiomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. The Oral Microbiome of King Richard III of England.American journal of biological anthropology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Irina M VelskoDepartment of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. irina_marie_velsko@eva.mpg.de.ORCID http://orcid.org/0000-0001-9810-9917
Christina WarinnerDepartment of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. warinner@fas.harvard.edu.

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) EXC2051 Project-ID 390713860
6 · The paper itself

Abstract

The genus Streptococcus is highly diverse and a core member of the primate oral microbiome. Streptococcus species are grouped into at least eight phylogenetically-supported clades, five of which are found almost exclusively in the oral cavity. We explored the dominant Streptococcus phylogenetic clades in samples from multiple oral sites and from ancient and modern-day humans and non-human primates and found that clade dominance is conserved across human oral sites, with most Streptococcus reads assigned to species falling in the Sanguinis or Mitis clades. However, minor differences in the presence and abundance of individual species within each clade differentiated human lifestyles, with loss of S. sinensis appearing to correlate with toothbrushing. Of the non-human primates, only baboons show clade abundance patterns similar to humans, suggesting that a habitat and diet similar to that of early humans may favor the growth of Sanguinis and Mitis clade species.

Indexed as

Host SpecificityLife StyleMouthPrimatesStreptococcusAnimalsDental CalculusDental PlaqueGenes, BacterialMicrobiota

Identifiers

PMID39824852
PMCPMC11748738

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.