Evidence map›Paper›PMID 39824721›Full record

ArticleTrends in cell biology2025

Fun in the sun: ribosomes defend against UV irradiation.

Aaztli R Coria, Emilien Orgebin, Colin Chih-Chien Wu

Abstract read
In one paragraph

Article in Trends in cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aaztli R CoriaCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA.
Emilien OrgebinCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA.
Colin Chih-Chien WuCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA. Electronic address: colin.wu2@nih.gov.

Funding

Ribosome quality controlZIABC012037 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WU, COLIN · 2021 to 2025
$7.1M
Intramural NIH HHS ZIA BC012037
6 · The paper itself

Abstract

The concept that ribosomes are sensors of translational distress has sparked significant interest, although much of the research has been conducted in vitro. A new study by Vind et al. provides in vivo evidence that the ribotoxic stress response (RSR) serves as the first line of defense against ultraviolet (UV) radiation.

Indexed as

RibosomesUltraviolet RaysAnimalsHumansProtein Biosynthesisapoptosisinflammationribotoxic stress responseskinUV exposureZAKα

Identifiers

PMID39824721
PMCPMC11805609

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.