Evidence map›Paper›PMID 39824513›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2025

Estradiol levels are differentially associated with pulse wave velocity in trauma-exposed premenopausal women with and without PTSD.

Chasity Corbin, Chowdhury Ibtida Tahmin, Chowdhury Tasnova Tahsin, Zynab Ahmed, Redeat Wattero, Azhaar Mohamed, Susan B Racette, Daniel Duprez, Ida T Fonkoue

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Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Chasity CorbinDivision of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota, United States.ORCID 0000-0003-4708-8380
Chowdhury Ibtida TahminDivision of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota, United States.
Chowdhury Tasnova TahsinDivision of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota, United States.ORCID 0009-0002-2914-4174
Zynab AhmedDivision of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota, United States.
Redeat WatteroDivision of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota, United States.ORCID 0009-0002-9548-3764
Azhaar MohamedDivision of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota, United States.
Susan B RacetteCollege of Health Solutions, Arizona State University, Phoenix, Arizona, United States.ORCID 0000-0002-6932-1887
Daniel DuprezDivision of Epidemiology and Community Health, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States.
Ida T FonkoueDivision of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota, United States.ORCID 0000-0003-3282-5739

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
VNS Modulation of the Central Autonomic Network and its Effects on ANSU54AT012307 · NCCIH · UNIVERSITY OF MINNESOTA · PI NAHAS, ZIAD · 2022 to 2024
$21.6M
Autonomic and Vascular Mechanisms of Cardiovascular Risk in Women with Post-traumatic Stress Disorder (PTSD)K01HL161027 · NHLBI · UNIVERSITY OF MINNESOTA · PI FONKOUE, IDA TCHUISSEU · 2022 to 2025
$529k
Longitudinal changes in vascular and autonomic function in premenopausal women with PTSDR03HL174817 · NHLBI · UNIVERSITY OF MINNESOTA · PI FONKOUE, IDA TCHUISSEU · 2024 to 2025
$213k
HHS | NIH | National Center for Advancing Translational Sciences (NCATS) UL1TR002494HHS | NIH | National Center for Complementary and Integrative Health (OAM) U54AT012307HHS | NIH | NHLBI | Division of Intramural Research (DIR) K01HL161027NCATS NIH HHS UL1 TR002494NCCIH NIH HHS U54 AT012307NHLBI NIH HHS K01 HL161027NHLBI NIH HHS R03 HL174817
6 · The paper itself

Abstract

Arterial stiffness is a well-known risk factor for cardiovascular disease. Although estradiol (E2) is known to be cardioprotective, the available data point to a growing cardiovascular disease risk in women before menopause due to posttraumatic stress disorder (PTSD). The present study aimed to investigate the effects of E2 on arterial compliance in trauma-exposed premenopausal women, with and without a clinical diagnosis of PTSD. We hypothesized that E2 will be differentially associated with pulse wave velocity (PWV) in women with PTSD (PTSD

Indexed as

EstradiolPremenopausePulse Wave AnalysisStress Disorders, Post-TraumaticVascular StiffnessAdultBiomarkersCase-Control StudiesFemaleHumansMiddle AgedBiomarkersEstradiolestradiolposttraumatic stress disorderpremenopausalpulse wave velocitywomen

Identifiers

PMID39824513
PMCPMC12167166

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.