Evidence map›Paper›PMID 39823552›Full record

ArticleACS applied bio materials2025

Exploring the Unique Properties and Superior Schwann Cell Guiding Abilities of Spider Egg Sac Silk.

Karolina Peter, Sarah Stadlmayr, Aida Naghilou, Leon Ploszczanski, Manuel Hofmann, Christian Riekel, Jiliang Liu, Manfred Burghammer, Claudia Gusenbauer, Johannes Konnerth and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Karolina PeterInstitute of Physics and Materials Science, Department of Natural Sciences and Sustainable Ressources, BOKU University, Peter Jordan-Straß 82, 1190 Vienna, Austria.ORCID 0000-0001-6288-7979
Sarah StadlmayrDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.ORCID 0000-0002-1461-6274
Aida NaghilouDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
Leon PloszczanskiInstitute of Physics and Materials Science, Department of Natural Sciences and Sustainable Ressources, BOKU University, Peter Jordan-Straß 82, 1190 Vienna, Austria.
Manuel HofmannDepartment of Physical Chemistry, University of Vienna, Währinger Str. 42, 1090 Vienna, Austria.
Christian RiekelEuropean Synchrotron Radiation Facility, 71 avenue des Martyrs, 38000 Grenoble, France.ORCID 0000-0003-2025-5118
Jiliang LiuEuropean Synchrotron Radiation Facility, 71 avenue des Martyrs, 38000 Grenoble, France.
Manfred BurghammerEuropean Synchrotron Radiation Facility, 71 avenue des Martyrs, 38000 Grenoble, France.
Claudia GusenbauerInstitute of Wood Technology and Renewable Materials, Department of Natural Sciences and Sustainable Resources, BOKU University, Konrad-Lorenz-Str. 24, 3430 Tulln an der Donau, Austria.ORCID 0000-0003-3520-3732
Johannes KonnerthInstitute of Wood Technology and Renewable Materials, Department of Natural Sciences and Sustainable Resources, BOKU University, Konrad-Lorenz-Str. 24, 3430 Tulln an der Donau, Austria.ORCID 0000-0003-3826-8566
Hannes C SchnieppDepartment of Applied Science, William & Mary, Williamsburg, Virginia 23185, United States.ORCID 0000-0003-4645-9469
Harald RennhoferInstitute of Physics and Materials Science, Department of Natural Sciences and Sustainable Ressources, BOKU University, Peter Jordan-Straß 82, 1190 Vienna, Austria.ORCID 0000-0003-0743-316X
Gerhard SinnInstitute of Physics and Materials Science, Department of Natural Sciences and Sustainable Ressources, BOKU University, Peter Jordan-Straß 82, 1190 Vienna, Austria.
Christine RadtkeDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
Helga C LichteneggerInstitute of Physics and Materials Science, Department of Natural Sciences and Sustainable Ressources, BOKU University, Peter Jordan-Straß 82, 1190 Vienna, Austria.

Funding

Austrian Science Fund FWF P 33613
6 · The paper itself

Abstract

Spider silk (SPSI) is a promising candidate for use as a filler material in nerve guidance conduits (NGCs), facilitating peripheral nerve regeneration by providing a scaffold for Schwann cells (SCs) and axonal growth. However, the specific properties of SPSI that contribute to its regenerative success remain unclear. In this study, the egg sac silk of

Indexed as

Biocompatible MaterialsSchwann CellsSilkSpidersAnimalsCells, CulturedMaterials TestingNerve RegenerationParticle SizeRatsTissue ScaffoldsBiocompatible MaterialsSilkMaterial CharacterizationMigratory BehaviorPeripheral Nerve RegenerationTubuliform silkX-ray Scattering

Identifiers

PMID39823552
PMCPMC11836930

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.