Evidence map›Paper›PMID 39823533›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Left Insula and Right Middle Temporal Gyrus Dominate Cortical Network Discriminating Arousal-dependent Emotions.

Na Clara Pan, Runshi Gao, Kai Ma, Liang Qiao, Duanyu Ni, Tao Yu, Yuping Wang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Na Clara PanDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Runshi GaoBeijing Key Laboratory of Neuromodulation, Beijing, 100053, China.
Kai MaBeijing Key Laboratory of Neuromodulation, Beijing, 100053, China.
Liang QiaoBeijing Key Laboratory of Neuromodulation, Beijing, 100053, China.
Duanyu NiBeijing Key Laboratory of Neuromodulation, Beijing, 100053, China.
Tao YuBeijing Key Laboratory of Neuromodulation, Beijing, 100053, China.
Yuping WangDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.ORCID https://orcid.org/0000-0002-6482-9710

Funding

National Key R&D Program 2021YFC2501400National Natural Science Foundation of China 82271494
6 · The paper itself

Abstract

Emotion processing is an integral part of everyone's life. The basic neural circuits involved in emotion perception are becoming clear, though the emotion's cognitive processing remains under investigation. Utilizing the stereo-electroencephalograph with high temporal-spatial resolution, this study aims to decipher the neural pathway responsible for discriminating low-arousal and high-arousal emotions. This study involves 19 patients with pharmacologically resistant epilepsy who participate in a delayed match/mismatch sample task designed to separately assess their ability to discriminate between low-arousal and high-arousal emotions. Three groups of 11 brain subregions, with dominant lateralization, compose a network, which is identified as responsible for discriminating arousal-dependent emotions. The connection of these subregions, leading by the left insula and right middle temporal gyrus, defines the pathways for discriminating emotions with different arousals. Further, the separated network patterns related to emotional discrimination are face-independent. Overall, the left insula and the right middle temporal gyrus emerge as core components in the network, which plays key roles in the dynamic course for discriminating low- and high-arousal emotions in the human brain.

Indexed as

ArousalCerebral CortexEmotionsInsular CortexNerve NetTemporal LobeAdultBrain MappingElectroencephalographyFemaleHumansMaleYoung Adultcognition controlelectrophysiologyemotion discriminationnetwork dynamicsneural basis

Identifiers

PMID39823533
PMCPMC11905088

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.