Evidence map›Paper›PMID 39823447›Full record

ArticlePloS one2025

Perceptions and practices of imaging personnel and physicians regarding the use of brain MRI for dementia diagnosis in Uganda.

Rita Nassanga, Noeline Nakasujja, Mark Kaddumukasa, Stephen E Jones, Martha Sajatovic, Michael Grace Kawooya

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rita NassangaDepartment of Radiology, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0001-7699-2155
Noeline NakasujjaDepartment of Psychiatry, College of Health Sciences, Makerere University, Kampala, Uganda.
Mark KaddumukasaDepartment of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Stephen E JonesImaging Institute, Cleveland Clinic Lerner School of Medicine, Cleveland, OH, United States of America.
Martha SajatovicCase Western Reserve University, Cleveland, OH, United States of America.
Michael Grace KawooyaErnest Cook Ultrasound Research and Education Institute (ECUREI), Kampala, Uganda.

Funding

NURTURE:Research Training and Mentoring Program for Career Development of Faculty at Makerere University College of Health SciencesD43TW010132 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2015 to 2019
$4.3M
Research training and mentorship to strengthen brain health across the lifespan in Uganda.D43NS118560 · NINDS · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KADDUMUKASA, MARK, KATABIRA, ELLY T · 2020 to 2024
$1.1M
FIC NIH HHS D43 TW010132NINDS NIH HHS D43 NS118560
6 · The paper itself

Abstract

introductionDiagnosing dementia remains challenging in low-income settings due to limited diagnostic options and the absence of definitive biomarkers. The use of brain MRI in the diagnosis of dementia is infrequent in Uganda, and even when it is used, subtle findings like mild regional atrophy are often overlooked, despite being crucial for imaging diagnosis.

objectiveThe purpose of this study was to explore the perceptions and practices of imaging personnel and physicians regarding the use of brain MRI as a diagnostic approach for dementia in Uganda.

methodsThis was an exploratory qualitative study involving radiologists, technologists, senior house officers and psychiatrists. The participants were 25 in total. Data was collected through key informant interviews and focus group discussions and analyzed thematically using an inductive approach.

resultsThe study revealed three key themes: Brain MRI Practices for Diagnosing Dementia, Facilitators of Appropriate MRI Use, and Barriers to Appropriate Use of Brain MRI. Sub-themes under these themes included cost considerations, poor and good MRI practices, MRI as a standard operating procedure, positive attitudes towards brain MRI, and barriers such as structural, financial, operational, technical, and patient-related issues. Participants acknowledged the high accuracy and superiority of brain MRI for diagnosing dementia and recognized it as the standard of care. However, its use in Uganda is limited due to high costs, restricted access, mechanical failures, patient claustrophobia, myths and misconceptions, and interpretation difficulties by radiologists and inappropriate protocols by technologists.

conclusionThe study identifies barriers to effective brain MRI use for dementia diagnosis in Uganda, including limited training, high costs, and uneven equipment distribution. Despite this, providers are positive about MRI adoption. Enhancing training, awareness, and phased rollouts can improve outcomes. Future research should focus on similar low-resource settings for validation.

Indexed as

BrainDementiaMagnetic Resonance ImagingPhysiciansAdultAttitude of Health PersonnelFemaleFocus GroupsHumansMaleMiddle AgedQualitative ResearchUganda

Identifiers

PMID39823447
PMCPMC11741567

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.