Evidence map›Paper›PMID 39823407›Full record

ArticlePloS one2025

Artificial intelligence applied in identifying left ventricular walls in myocardial perfusion scintigraphy images: Pilot study.

Solange Amorim Nogueira, Fernanda Ambrogi B Luz, Thiago Fellipe O Camargo, Julio Cesar S Oliveira, Guilherme Carvalho Campos Neto, Felipe Brazao F Carvalhaes, Marcio Rodrigues C Reis, Paulo Victor Santos, Giovanna Souza Mendes, Rafael Maffei Loureiro and 4 more

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Solange Amorim NogueiraElectrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.ORCID 0000-0001-7481-7142
Fernanda Ambrogi B LuzElectrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.
Thiago Fellipe O CamargoElectrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.
Julio Cesar S OliveiraHospital Israelita Albert Einstein, Sao Paulo, Brazil.
Guilherme Carvalho Campos NetoHospital Israelita Albert Einstein, Sao Paulo, Brazil.
Felipe Brazao F CarvalhaesHospital Israelita Albert Einstein, Sao Paulo, Brazil.
Marcio Rodrigues C ReisElectrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.
Paulo Victor SantosElectrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.
Giovanna Souza MendesHospital Israelita Albert Einstein, Sao Paulo, Brazil.
Rafael Maffei LoureiroHospital Israelita Albert Einstein, Sao Paulo, Brazil.ORCID 0000-0002-1635-2225
Daniel TornieriHospital Israelita Albert Einstein, Sao Paulo, Brazil.
Viviane M Gomes PachecoElectrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.
Antonio Paulo CoimbraSystems and Robotics Institute, Coimbra University, Coimbra, Portugal.
Wesley Pacheco CalixtoElectrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.ORCID 0000-0002-1928-4432

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper proposes the use of artificial intelligence techniques, specifically the nnU-Net convolutional neural network, to improve the identification of left ventricular walls in images of myocardial perfusion scintigraphy, with the objective of improving the diagnosis and treatment of coronary artery disease. The methodology included data collection in a clinical environment, followed by data preparation and analysis using the 3D Slicer Platform for manual segmentation, and subsequently, the application of artificial intelligence models for automated segmentation, focusing on the efficiency of identifying the walls of the left ventricular. A total of 83 clinical routine exams were collected, each exam containing 50 slices, which is 4,150 images. The results demonstrate the efficiency of the proposed artificial intelligence model, with a Dice coefficient of 87% and an average Intersection over Union of 0.8, reflecting high agreement with the manual segmentations produced by experts and surpassing traditional interpretation methods. The internal and external validation of the model corroborates its future applicability in real clinical scenarios, offering a new perspective in the analysis of myocardial perfusion scintigraphy images. The integration of artificial intelligence into the process of analyzing myocardial perfusion scintigraphy images represents a significant advancement in diagnostic accuracy, promoting substantial improvements in the interpretation of medical images, and establishing a foundation for future research and clinical applications, such as artifact correction.

Indexed as

Artificial IntelligenceCoronary Artery DiseaseHeart VentriclesMyocardial Perfusion ImagingAgedFemaleHumansMaleMiddle AgedNeural Networks, ComputerPilot Projects

Identifiers

PMID39823407
PMCPMC11741626

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.