Evidence map›Paper›PMID 39823335›Full record

ArticleScience advances2025

Inherent differential microbial assemblages and functions associated with corals exhibiting different thermal phenotypes.

Erika P Santoro, Anny Cárdenas, Helena D M Villela, Caren L S Vilela, Angela M Ghizelini, Gustavo A S Duarte, Gabriela Perna, João P Saraiva, Torsten Thomas, Christian R Voolstra and 1 more

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Erika P SantoroDivision of Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.ORCID 0000-0002-4962-1356
Anny CárdenasDepartment of Biology, University of Konstanz, Konstanz, Germany.ORCID 0000-0002-4080-9010
Helena D M VillelaDivision of Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.ORCID 0000-0002-0052-503X
Caren L S VilelaIMPPG, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0001-5959-7436
Angela M GhizeliniIMPPG, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0003-4115-2177
Gustavo A S DuarteDivision of Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.ORCID 0000-0002-7950-3975
Gabriela PernaDepartment of Biology, University of Konstanz, Konstanz, Germany.ORCID 0000-0003-1197-9560
João P SaraivaDepartment of Environmental Microbiology, Helmholtz Center for Environmental Research - UFZ, Leipzig, Germany.
Torsten ThomasCenter for Marine Science and Innovation, School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, Australia.
Christian R VoolstraDepartment of Biology, University of Konstanz, Konstanz, Germany.ORCID 0000-0003-4555-3795
Raquel S PeixotoDivision of Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.ORCID 0000-0002-9536-3132

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Certain coral individuals exhibit enhanced resistance to thermal bleaching, yet the specific microbial assemblages and their roles in these phenotypes remain unclear. We compared the microbial communities of thermal bleaching-resistant (TBR) and thermal bleaching-sensitive (TBS) corals using metabarcoding and metagenomics. Our multidomain approach revealed stable distinct microbial compositions between thermal phenotypes. Notably, TBR corals were inherently enriched with microbial eukaryotes, particularly Symbiodiniaceae, linked to photosynthesis, and the biosynthesis of antibiotic and antitumor compounds and glycosylphosphatidylinositol-anchor proteins, crucial for cell wall regulation and metabolite exchange. In contrast, TBS corals were dominated by bacterial metabolic genes related to nitrogen, amino acid, and lipid metabolism. The inherent microbiome differences between TBR and TBS corals, already observed before thermal stress, point to distinct holobiont phenotypes associated to thermal bleaching resistance, offering insights into mechanisms underlying coral response to climate-induced stress.

Indexed as

AnthozoaMicrobiotaAnimalsBacteriaMetagenomicsPhenotypeSymbiosisTemperature

Identifiers

PMID39823335
PMCPMC11740947

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.