Evidence map›Paper›PMID 39823182›Full record

SynthesisPediatric obesity2025

Effectiveness of behavioural and psychological interventions for managing obesity in children and adolescents: A systematic review and meta-analysis framed using minimal important difference estimates based on GRADE guidance to inform a clinical practice guideline.

M Henderson, S A Moore, S Harnois-Leblanc, B C Johnston, D Fitzpatrick-Lewis, A M Usman, D Sherifali, R Merdad, A M Rigsby, Z Esmaeilinezhad and 5 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Pediatric obesity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  3. Managing obesity in children: a clinical practice guideline.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

M HendersonSainte-Justine University Hospital Research Center, Université de Montréal, Montréal, Quebec, Canada.ORCID https://orcid.org/0000-0002-0102-2389
S A MooreSchool of Health and Human Performance, Faculty of Health, Dalhousie University, Halifax, Nova Scotia, Canada.
S Harnois-LeblancSainte-Justine University Hospital Research Center, Université de Montréal, Montréal, Quebec, Canada.
B C JohnstonDepartment of Nutrition, College of Agriculture and Life Science, Texas A&M University, College Station, Texas, USA.
D Fitzpatrick-LewisSchool of Nursing, McMaster University, Hamilton, Ontario, Canada.
A M UsmanMcMaster Evidence Review and Synthesis Team, McMaster University, Hamilton, Ontario, Canada.
D SherifaliSchool of Nursing, McMaster University, Hamilton, Ontario, Canada.
R MerdadDepartment of Community Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
A M RigsbyDepartment of Nutrition, College of Agriculture and Life Science, Texas A&M University, College Station, Texas, USA.
Z EsmaeilinezhadDepartment of Nutrition, College of Agriculture and Life Science, Texas A&M University, College Station, Texas, USA.
K M MorrisonDepartment of Pediatrics, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0002-1737-256X
J HamiltonThe Hospital for Sick Children, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-1958-2800
G D C BallDepartment of Pediatrics, Faculty of Medicine & Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.ORCID https://orcid.org/0000-0002-9432-3120
C S BirkenDepartment of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
Steering Committee for Updating Canada's Clinical Practice Guideline for Managing Pediatric Obesity

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveConduct a systematic review and meta-analysis of randomized controlled trials (RCTs) of behavioural and psychological interventions for managing paediatric obesity.

methodsEligible studies, published between 1985 and 2022, included 0 to 18 year olds with outcomes reported ≥3 months post-baseline, including patient-reported outcome measures (PROMs), cardiometabolic and anthropometric outcomes, and adverse events (AEs). We pooled data using a random effects model and assessed certainty of evidence (CoE) related to minimally important difference estimates for outcomes using GRADE.

resultsWe included 73 unique RCTs (n = 6305 participants, 53% female). Intervention types included physical activity (n = 1437), nutrition (n = 447), psychological (n = 1336), technology-based (n = 901) or multicomponent (≥2 intervention types, n = 2184). Physical activity had a small effect on health-related quality of life (HRQoL), varying effects ranging from moderate to very large on blood pressure, lipids and insulin resistance, and a small effect on BMIz. Nutrition had a small effect on lipids, insulin resistance and BMIz. Psychological interventions showed a small effect on HRQoL and triglycerides and moderate benefits on depressive symptoms, while technology interventions showed small benefits on blood pressure and BMIz. Multicomponent interventions had a large benefit on anxiety, small benefit on depressive symptoms, with large to very large benefits on lipids, and small benefits for diastolic blood pressure, insulin resistance and BMIz. AEs were reported infrequently, and when reported, were described as mild.

conclusionPhysical activity and multicomponent interventions showed improvements in PROMs, cardiometabolic and anthropometric outcomes. Future trials should consistently measure PROMs, evaluate outcomes beyond the intervention period, and study children <6 years of age.

Indexed as

Behavior TherapyPediatric ObesityPsychosocial InterventionAdolescentChildChild, PreschoolExerciseFemaleHumansMalePractice Guidelines as TopicQuality of LifeRandomized Controlled Trials as TopicTreatment Outcomebehavioural interventionslifestyle interventionsmeta‐analysispaediatric obesityrandomized controlled trialssystematic review

Identifiers

PMID39823182
PMCPMC11803187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.