Evidence map›Paper›PMID 39823111›Full record

ArticleJournal of clinical and translational science2024

Predictors of willingness to participate in COVID-19 clinical trials among Black and Latino adults.

Christine M Weston, Elizabeth L Andrade, Wuraola Olawole, Monica Guerrero Vazquez, Hailey Miller, Sarah C Stevens, Cyd Lacanienta, Nancy Perrin, Mark C Edberg, Thomas A Mellman and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and translational science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Christine M WestonJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.ORCID https://orcid.org/0009-0003-6212-1086
Elizabeth L AndradeGeorge Washington University Milken Institute School of Public Health, Washingon, DC, USA.
Wuraola OlawoleJohns Hopkins University School of Nursing, Baltimore, MD, USA.
Monica Guerrero VazquezJohns Hopkins University Centro SOL, Baltimore, MD, USA.
Hailey MillerJohns Hopkins University School of Nursing, Baltimore, MD, USA.
Sarah C StevensJohns Hopkins University Institute for Clinical and Translational Research, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-7599-0729
Cyd LacanientaJohns Hopkins University Institute for Clinical and Translational Research, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-3840-0822
Nancy PerrinHoward University, Washington, DC, USA.
Mark C EdbergGeorge Washington University Milken Institute School of Public Health, Washingon, DC, USA.
Thomas A MellmanHoward University, Washington, DC, USA.
Yvonne BronnerMorgan State University, Baltimore, MD, USA.
Roger ClarkJohns Hopkins University Institute for Clinical and Translational Research, Baltimore, MD, USA.
Cheryl R Dennison HimmelfarbJohns Hopkins University School of Nursing, Baltimore, MD, USA.

Funding

QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
NCATS NIH HHS UL1 TR003098
6 · The paper itself

Abstract

Introduction: Black and Latino individuals are underrepresented in COVID-19 treatment and vaccine clinical trials, calling for an examination of factors that may predict willingness to participate in trials. Methods: We administered the Common Survey 2.0 developed by the Community Engagement Alliance (CEAL) Against COVID-19 Disparities to 600 Black and Latino adults in Baltimore City, Prince George's County, Maryland, Montgomery County, Maryland, and Washington, DC, between October and December 2021. We examined the relationship between awareness of clinical trials, social determinants of health challenges, trust in COVID-19 clinical trial information sources, and willingness to participate in COVID-19 treatment and vaccine trials using multinomial regression analysis. Results: Approximately half of Black and Latino respondents were unwilling to participate in COVID-19 treatment or vaccine clinical trials. Results showed that increased trust in COVID-19 clinical trial information sources and trial awareness were associated with greater willingness to participate in COVID-19 treatment and vaccine trials among Black and Latino individuals. For Latino respondents, having recently experienced more challenges related to social determinants of health was associated with a decreased likelihood of willingness to participate in COVID-19 vaccine trials. Conclusions: The willingness of Black and Latino adults to participate in COVID-19 treatment and vaccine clinical trials is influenced by trial awareness and trust in trial information sources. Ensuring the inclusion of these communities in clinical trials will require approaches that build greater awareness and trust.

Indexed as

African Americans/Blacksclinical trial participationCOVID-19Latinossocial determinants of health

Identifiers

PMID39823111
PMCPMC11736297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.