Evidence map›Paper›PMID 39822952›Full record

ReviewDEN open2025

Endoscopic diagnosis and management of eosinophilic esophagitis.

Fumio Tanaka, Akinari Sawada, Sayaka Tanaka, Kenichi Kohashi, Yasuhiro Fujiwara

Abstract readReview
In one paragraph

Review in DEN open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fumio TanakaDepartment of Gastroenterology Graduate School of Medicine Osaka Metropolitan University Osaka Japan.ORCID https://orcid.org/0000-0002-9186-1249
Akinari SawadaDepartment of Gastroenterology Graduate School of Medicine Osaka Metropolitan University Osaka Japan.
Sayaka TanakaDepartment of Pathology Graduate School of Medicine Osaka Metropolitan University Osaka Japan.
Kenichi KohashiDepartment of Pathology Graduate School of Medicine Osaka Metropolitan University Osaka Japan.
Yasuhiro FujiwaraDepartment of Gastroenterology Graduate School of Medicine Osaka Metropolitan University Osaka Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic esophagitis is a chronic allergic inflammatory disease, and its incidence and prevalence have recently increased. Eosinophilic esophagitis has not become a rare disease; thus, knowledge for diagnosing it is needed in current clinical practice. The adequate management of endoscopic procedures is particularly important for the diagnosis and evaluation of inflammatory activity and therapeutic responses. The therapeutic options for eosinophilic esophagitis include anti-acid drugs such as proton pump inhibitors, potassium-competitive acid blockers, swallowed topical corticosteroids, biologics, and dietary elimination therapies. Moreover, endoscopic esophageal dilation is a therapeutic option for fibrotic strictures due to eosinophilic esophagitis to improve obstructive symptoms, such as dysphagia and food impaction. In this review, we describe the endoscopic characteristics of eosinophilic esophagitis, including an endoscopic reference score and an optimal biopsy protocol to diagnose and evaluate the therapeutic response. We also describe a current therapeutic management of eosinophilic esophagitis.

Indexed as

diagnosisendoscopyeosinophilic esophagitiseosinophilstherapeutics

Identifiers

PMID39822952
PMCPMC11736424

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.