Evidence map›Paper›PMID 39822823›Full record

ArticleJACC. Case reports2025

Surgical Management of Fibrosing Mediastinitis Presenting as Superior Vena Cava Syndrome.

Ye In Christopher Kwon, Michelle Burmistrova, Ahmet Kilic

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ye In Christopher KwonSchool of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Michelle BurmistrovaAlbany Medical College, Albany, New York, USA.
Ahmet KilicDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibrosing mediastinitis is a rare chronic inflammatory condition characterized by excessive fibrotic process in the mediastinum. Although various infectious processes are more common causes, it can also be related to several malignancies. We report a case of a 28-year-old woman with fibrosing mediastinitis related to an aggressive primary gray-zone lymphoma causing complete occlusion of the superior vena cava (SVC) and the innominate veins. She underwent several unsuccessful attempts at stenting and angioplasty. Due to worsening symptoms of SVC syndrome, she was ultimately treated with surgical reconstruction of the SVC and innominate veins using the Y-synthetic graft technique. A high degree of clinical suspicion should be maintained to diagnose fibrosing mediastinitis in onco-cardiovascular patients. With careful patient selection, review of techniques and imaging, surgical reconstruction may be a viable strategy for patients with SVC syndrome secondary to malignancy who have exhausted endovascular options.

Indexed as

fibrosing mediastinitismediastinal gray-zone lymphomasuperior vena cava syndrome

Identifiers

PMID39822823
PMCPMC11733603

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.