A survey of lip lesions diagnosed in a single institution: A clinicopathological study.

Background: The aim of this study was to assess the clinicopathological features of lip lesions diagnosed in a single Oral Pathology service in Brazil. Material and Methods: It was a cross-sectional study based on secondary data. Between 2000 and 2019, all lip lesions diagnosed in an Oral Pathology service in Brazil were analyzed. Clinical and demographic data, such as patient age and gender, general habits, location, clinical hypotheses of diagnosis, and biopsy type, were collected from patients' clinical records. All cases were microscopically reviewed. Descriptive statistics were obtained for all described variables. Subsequently, associations between variables and identified lesion groups were performed. The KAPPA test was used to assess the agreement between clinical and histopathological diagnoses. Results: A total of 1,284 cases were analyzed, representing 17.8% of oral lesions. The most prevalent lesions were: mucocele (32.9%), fibrous hyperplasia (15.7%), non-specific chronic sialadenitis (11.1%), and actinic cheilitis (9.6%). The demographic distribution included 740 women (61%) and 472 men (39%). The mean age was 37.6 years (ranging from 3 to 97 years). The primary site of presentation was the lower lip, with 980 cases (86.7%). In 783 cases (64.5%), there was concordance between the clinical and histopathological diagnoses. Conclusions: Lip is a significant region for oral diseases, representing approximately 20% of all oral lesions. Importantly, more than 10% of the cases were oral potentially malignant disorders or malignant neoplasms.