Evidence map›Paper›PMID 39822719›Full record

ArticleACS sustainable chemistry & engineering2025

Rapid and Green Anion-Assisted Mechanochemical Peptide Cyclization.

Mirko Duvnjak, Nikolina Vidović, Krunoslav Užarević, Gordan Horvat, Vladislav Tomišić, Giovanna Speranza, Nikola Cindro

Abstract read
In one paragraph

Article in ACS sustainable chemistry & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mirko DuvnjakDepartment of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.
Nikolina VidovićFaculty of Biotechnology and Drug Development, University of Rijeka, R. Matejčić 2, 51000 Rijeka, Croatia.ORCID https://orcid.org/0000-0003-0710-143X
Krunoslav UžarevićRuđer Bošković Institute, Bijenička c. 54, 10000 Zagreb, Croatia.ORCID https://orcid.org/0000-0002-7513-6485
Gordan HorvatDepartment of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.
Vladislav TomišićDepartment of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.ORCID https://orcid.org/0000-0002-1191-2123
Giovanna SperanzaDepartment of Chemistry, University of Milan, Via C. Golgi 19, 20133 Milan, Italy.ORCID https://orcid.org/0000-0003-4544-1515
Nikola CindroDepartment of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.ORCID https://orcid.org/0000-0001-9299-5815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel mechanochemical approach is described for chloride-templated head-to-tail macrocyclization of a pentapeptide and a hexapeptide. This straightforward method allows the solvent-free preparation of cyclopeptides with yields comparable to solution-based approaches without the need for high dilution of the reaction mixture and with significantly reduced reaction times and organic waste amount.

Identifiers

PMID39822719
PMCPMC11734432

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.