Evidence map›Paper›PMID 39822585›Full record

ArticleHemaSphere2025

Idecabtagene vicleucel or ciltacabtagene autoleucel for relapsed or refractory multiple myeloma: An international multicenter study.

Maximilian Merz, Anca-Maria Albici, Bastian von Tresckow, Kristin Rathje, Roland Fenk, Tobias Holderried, Fabian Müller, Natalia Tovar, Aina Oliver-Cáldes, Vladan Vucinic and 19 more

Abstract read
In one paragraph

Article in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  20. 2025 Update of Cellular Immunotherapy for Plasma Cell Disorders.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Maximilian MerzDepartment of Hematology, Cellular Therapy, Hemostaseology and Infectious Diseases Universitätsklinikum Leipzig Leipzig Germany.ORCID 0000-0002-2805-5973
Anca-Maria AlbiciKlinik für Innere Medizin II - Hämatologie, Onkologie, University Hospital Schleswig-Holstein Kiel Kiel University Kiel Germany.
Bastian von TresckowDepartment of Haematology and Stem Cell Transplantation, West German Cancer Center and German Cancer Consortium (DKTK partner site Essen), University Hospital Essen University of Duisburg-Essen Essen Germany.
Kristin RathjeInterdisziplinäre Klinik und Poliklinik für Stammzelltransplantation University Medical Center Hamburg-Eppendorf Hamburg Germany.
Roland FenkKlinik für Hämatologie, Onkologie und Klinische Immunologie, Heinrich Heine University University Hospital Düsseldorf Düsseldorf Germany.
Tobias HolderriedMedizinische Klinik und Poliklinik III - Innere Medizin mit den Schwerpunkten Onkologie, Hämatologie, Immunonkologie und Rheumatologie Universitätsklinikum Bonn Bonn Germany.
Fabian MüllerDepartment of Internal Medicine 5, Haematology and Oncology, University Hospital of Erlangen Friedrich-Alexander University of Erlangen-Nuremberg (FAU) Erlangen Germany.ORCID 0000-0001-5487-5839
Natalia TovarInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) Hospital Clínic de Barcelona Barcelona Spain.
Aina Oliver-CáldesInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) Hospital Clínic de Barcelona Barcelona Spain.
Vladan VucinicDepartment of Hematology, Cellular Therapy, Hemostaseology and Infectious Diseases Universitätsklinikum Leipzig Leipzig Germany.ORCID 0000-0002-8398-285X
Soraya KharboutliDepartment of Internal Medicine 5, Haematology and Oncology, University Hospital of Erlangen Friedrich-Alexander University of Erlangen-Nuremberg (FAU) Erlangen Germany.
Ben-Niklas BärmannKlinik für Hämatologie, Onkologie und Klinische Immunologie, Heinrich Heine University University Hospital Düsseldorf Düsseldorf Germany.
Francis AyukInterdisziplinäre Klinik und Poliklinik für Stammzelltransplantation University Medical Center Hamburg-Eppendorf Hamburg Germany.
Uwe PlatzbeckerDepartment of Hematology, Cellular Therapy, Hemostaseology and Infectious Diseases Universitätsklinikum Leipzig Leipzig Germany.
Friedrich StölzelKlinik für Innere Medizin II - Hämatologie, Onkologie, University Hospital Schleswig-Holstein Kiel Kiel University Kiel Germany.
Nathalie SchubKlinik für Innere Medizin II - Hämatologie, Onkologie, University Hospital Schleswig-Holstein Kiel Kiel University Kiel Germany.
Friederike SchmitzMedizinische Klinik und Poliklinik III - Innere Medizin mit den Schwerpunkten Onkologie, Hämatologie, Immunonkologie und Rheumatologie Universitätsklinikum Bonn Bonn Germany.
David FandreiDepartment of Hematology, Cellular Therapy, Hemostaseology and Infectious Diseases Universitätsklinikum Leipzig Leipzig Germany.
Patrick BornDepartment of Hematology, Cellular Therapy, Hemostaseology and Infectious Diseases Universitätsklinikum Leipzig Leipzig Germany.
Cyrus KhandanpourKlinik für Hämatologie und Onkologie University Hospital Lübeck Lübeck Germany.
Christine HanounDepartment of Haematology and Stem Cell Transplantation, West German Cancer Center and German Cancer Consortium (DKTK partner site Essen), University Hospital Essen University of Duisburg-Essen Essen Germany.ORCID 0000-0003-2766-1696
Keven HörsterDepartment of Haematology and Stem Cell Transplantation, West German Cancer Center and German Cancer Consortium (DKTK partner site Essen), University Hospital Essen University of Duisburg-Essen Essen Germany.
Marcel TeichertDepartment of Haematology and Stem Cell Transplantation, West German Cancer Center and German Cancer Consortium (DKTK partner site Essen), University Hospital Essen University of Duisburg-Essen Essen Germany.
Barbara JekerUniversitätsklinik für Medizinische Onkologie, Inselspital Bern University Hospital, Bern Bern Schweiz.
Michele HoffmannUniversitätsklinik für Medizinische Onkologie, Inselspital Bern University Hospital, Bern Bern Schweiz.
Nicolaus KrögerInterdisziplinäre Klinik und Poliklinik für Stammzelltransplantation University Medical Center Hamburg-Eppendorf Hamburg Germany.
Carlos Fernández de LarreaInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) Hospital Clínic de Barcelona Barcelona Spain.ORCID 0000-0003-4930-9255
Thomas PabstUniversitätsklinik für Medizinische Onkologie, Inselspital Bern University Hospital, Bern Bern Schweiz.
Nico GagelmannInterdisziplinäre Klinik und Poliklinik für Stammzelltransplantation University Medical Center Hamburg-Eppendorf Hamburg Germany.ORCID https://orcid.org/0000-0002-0891-1744

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idecabtagene vicleucel (ide-cel) and ciltacabtagene autoleucel (cilta-cel) have revolutionized the treatment of relapsed/refractory multiple myeloma (RRMM), but direct comparisons are lacking. Leveraging an international multicenter RRMM cohort, we compared the outcome of ide-cel (

Identifiers

PMID39822585
PMCPMC11735948

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.