Evidence map›Paper›PMID 39822532›Full record

ReviewAmerican journal of translational research2024

Effectiveness of bundle of His pacing for cardiac resynchronization therapy in patients with heart failure combined with wide QRS complex: a meta-analysis.

Zhigang You, Hui Wang, Lin Huang

Abstract readReview
In one paragraph

Review in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhigang YouDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University Nanchang 330006, Jiangxi, China.
Hui WangInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences Beijing 100101, China.
Lin HuangDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University Nanchang 330006, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate systematically the feasibility and effectiveness of His Bundle Pacing (HBP) for cardiac resynchronization therapy.

methodsA comprehensive search was conducted in PubMed, EMbase, WOS, Cochrane Library, Medline, and SinoMed for studies published between December 2003 and December 2023. Primary clinical outcomes included implantation success, QRS wave duration, pacing threshold, left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVEDD), New York Heart Association (NYHA) cardiac function class, and complications. Data were extracted and summarized, and meta-analysis was performed by Revman 5.3 software.

resultsFourteen studies involving a total of 555 patients were included. The overall success rate for HBP implantation was 83.2% (462/555). Compared to baseline values, QRS duration was significantly reduced (MD=48.29, 95% CI: 45.20 to 51.38, P<0.01, I

conclusionHBP is effective for cardiac resynchronization therapy. HBP significantly reduces QRS duration and improves LVEF in heart failure patients.

Indexed as

cardiac resynchronization therapyHis bundle pacingmeta-analysisventricular pacingwide QRS wave

Identifiers

PMID39822532
PMCPMC11733384

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.