ArticleAmerican journal of translational research2024
Influencing factors on neurological prognosis after traumatic brain injury and the role of brain tissue oxygen pressure (PbtO
Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo identify factors influencing neurological prognosis following traumatic brain injury (TBI) and to analyze the role of brain tissue oxygen pressure (PbtO
methodsIn this case-control study, medical records of 412 individuals diagnosed with TBI were thoroughly examined and analyzed. The patients were divided into two groups based on their prognosis at three months post-injury: Good Prognosis (n = 321) and Poor Prognosis (n = 91). Demographic and clinical characteristics, brain tissue oxygen partial pressure, radiological and laboratory findings, treatment interventions, and complications were compared between the two groups. Logistic regression analysis was conducted to identify the risk factors for neurological prognosis, and the predictive value of these factors was evaluated using receiver operating characteristic (ROC) curve analysis.
resultsThe study identified associations between Injury Severity Score (ISS), Glasgow Coma Scale (GCS), PbtO
conclusionThe study highlights the prognostic significance of injury severity, brain tissue oxygenation, radiological findings, and laboratory parameters in determining neurological outcomes following TBI. Furthermore, the findings emphasize the potential of PbtO
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