Evidence map›Paper›PMID 39822483›Full record

ArticleAmerican journal of translational research2024

Use of the flexible vacuum-assisted ureteral access sheath combined with flexible ureteroscope for patients with large renal stones.

Dong Li, Jinfeng Yu, Yirun Chen, Jia'neng Xu, Jinfeng Zhang

Abstract read
In one paragraph

Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Dong LiDepartment of Urinary Surgery, The First People's Hospital of Jiashan Jiaxing, Zhejiang, China.
Jinfeng YuDepartment of Urinary Surgery, The First People's Hospital of Jiashan Jiaxing, Zhejiang, China.
Yirun ChenDepartment of Urinary Surgery, The First People's Hospital of Jiashan Jiaxing, Zhejiang, China.
Jia'neng XuDepartment of Urinary Surgery, The First People's Hospital of Jiashan Jiaxing, Zhejiang, China.
Jinfeng ZhangDepartment of Urinary Surgery, Jiashan County Chinese Medicine Hospital Jiaxing, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effects and safety of the flexible vacuum-assisted ureteral access sheath combined with a flexible ureteroscope for the treatment of large renal stones over 3 cm.

methodsIn this retrospective study, 122 patients with kidney stones (stone diameter ≥ 3 cm) admitted to our hospital from January 2018 to December 2022 were selected as the study subjects. According to different surgical methods, these patients were divided into an observation group and a control group, with 61 cases in each group. Patients in the control group were treated with the conventional negative pressure-assisted ureteral access sheath combined with flexible ureteroscope, while those in the observation group were treated with the flexible vacuum-assisted ureteral access sheath combined with flexible ureteroscope. The perioperative indexes, stone-free rate, usage rate of basket extraction, inflammation level, renal functional indexes, and incidence of postoperative complications were evaluated and compared between the two groups.

resultsThe extubation time, rate of multiple operations, and surgery cost in the observation group were significantly less than those of the control group (all P < 0.05), but the operation time was longer in the observation group than that of the control group (P < 0.05). The stone-free rate at 3 days after surgery in the observation group was higher than that of the control group, while the usage rate of basket extraction of the observation group was significantly less than that of the control group (all P < 0.05). The postoperative levels of C-reactive protein (CRP) and Interleukin (IL)-6 were significantly lower, while the level of IL-10 was significantly higher in the observation group than in the control group (all P < 0.001). The levels of renal functional indexes such as CysC, Scr, and KIM-1 in the observation group were lower than those of the control group (all P < 0.05). The total incidence of postoperative complications in the observation group was 8.20%, which was lower than 24.59% in the control group (P = 0.014). Moreover, postoperative sleep quality was better, and the comfort score was higher in the observation group than that of the control group (all P < 0.001).

conclusionThe flexible vacuum-assisted ureteral access sheath combined with flexible ureteroscope is effective in the treatment of large renal stones over 3 cm, and may improve the perioperative indexes, postoperative sleep quality and comfort, increase the stone-free rate, alleviate the inflammation levels and kidney functional injury, and reduce the incidence of complications.

Indexed as

complicationflexible ureteroscopyinflammatory factorkidney functionRenal stoneureter access sheath

Identifiers

PMID39822483
PMCPMC11733324

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.