Evidence map›Paper›PMID 39822474›Full record

ArticleCureus2024

Association of the Triglyceride Glucose Index With Outcomes in Acute Ischemic Stroke Injury.

Rishita Garg, Mini Bhatnagar, Sunita Gupta

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rishita GargGeneral Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, IND.
Mini BhatnagarGeneral Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, IND.
Sunita GuptaGeneral Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives The study aimed at estimating the triglyceride glucose (TyG) index in patients with ischemic stroke, exploring the correlation between the TyG index and the prognosis of ischemic stroke, and studying the clinical outcome in patients with acute ischemic stroke (AIS) in association with the TyG index. Methods An observational study was conducted on 105 patients with a history of AIS presenting within 24 hours. The TyG index was estimated, and the clinical outcome was studied. The outcome measures were neurological worsening (National Institutes of Health Stroke Scale (NIHSS) >=2 gain at discharge above admission), poor functional outcomes (assessed by derangement of modified Rankin scale (mRS) at three months), stroke recurrence, and three-month mortality rate. The NIHSS and mRS were assessed at admission, discharge, and three months later. Results The mean TyG index of AIS patients was 9.26±0.2. Compared to patients without neurological worsening (n=8), patients with neurological worsening had a significantly higher TyG index (9.5±0.19 vs. 9.21±0.21, p<.0001). Compared to patients without poor functional outcomes (n=20), patients with poor functional outcomes had a similar TyG index (9.31±0.31 vs. 9.25±0.22, p=0.418). Compared to patients without recurrence, those with recurrence of stroke had a significantly higher TyG index (9.55±0.18 vs. 9.15±0.15, p<.0001). On the follow-up of three months post-stroke, compared to survivors, non-survivors had a similar TyG index (9.12±0.25 vs. 9.27±0.24, p=0.09). Conclusion The TyG index showed a significant association with outcomes of AIS in terms of stroke recurrence and neurological worsening. Overall, it shows that insulin resistance has a significant impact on the neurological outcomes and recurrence of stroke in AIS patients.

Indexed as

aisneurological worseningoutcomesstroke prognosistriglyceride glucose index

Identifiers

PMID39822474
PMCPMC11735850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.