ArticleCureus2024
Comparison of Lignocaine-Dexamethasone vs. Lignocaine-Triamcinolone for Preventing Post Spinal-Epidural Backache: A Randomized Study.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Multifunctional Magnetic Nanoparticles for Targeted Drug Delivery Against Cancer: A Review of Mechanisms, Applications, Consequences, Limitations, and Tailoring Strategies.Annals of biomedical engineering · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe primary objective of this study was to compare the efficacy of lignocaine-dexamethasone and lignocaine-triamcinolone infiltration, along the spinal-epidural needle insertion pathway, to prevent backache after lower abdominal surgeries.
methodsThis prospective, double-blind randomized controlled study included a total of 150 patients, scheduled for elective lower abdominal surgery under combined spinal-epidural (CSE) anaesthesia. The patients were randomised into three groups Group L (Lignocaine, n=50), Group DL (Dexamethasone, Lignocaine, n=50), and Group TL (Triamcinolone, Lignocaine, n=50).
resultsThe Visual Analogue Score (VAS) was used to assess the postoperative pain. The anthropometric and demographic findings were comparable among the three groups. The mean VAS score at the time points of needle placement and at postoperative time periods of 24 hours, 48 hours, 72 hours, one month, two months and three months were significantly lower (p<0.001) in groups DL and TL compared to group L.
conclusionThis study demonstrated that the addition of a steroid like triamcinolone or dexamethasone with lignocaine for local infiltration along the spinal-epidural tract significantly lowers the severity of post-needle puncture backache in comparison to lignocaine alone in lower abdominal surgeries.
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Registered trials
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