ArticleGland surgery2024
Comparison of postoperative biochemical indicators and surgical result between partial adrenalectomy and total adrenalectomy: a systematic review and meta-analysis.
Article in Gland surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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12 authors.
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Abstract
Background: The selection and extent of application for both total adrenalectomy (TA) and partial adrenalectomy (PA) within this surgical approach continue to be matters of debate. This paper compares the postoperative efficacy and functional indicators of PA and TA to provide comprehensive insights for clinicians to consider the best surgical treatment options. Methods: Systematic review on PubMed, Embase, Cochrane Library, Web of Science, and China National Knowledge Infrastructure (CNKI) was conducted. We compared several key factors between TA and PA, including operating time (OT), blood loss, length of hospital stay, serum aldosterone levels, plasma renin activity, postoperative aldosterone to renin ratio (ARR), systolic and diastolic blood pressure, early postoperative complications, and blood potassium concentration. Data were collected by the Cochran-Mantel-Haenszel method, and Review Manager software (RevMan) version 5.3 was used. Results: The results showed that compared to TA, PA had a shorter OT [weighted mean difference (WMD) =-12.16; 95% confidence interval (CI): -19.42, -4.89; I Conclusions: The OT was shorter in PA than in TA, and shorter in younger patients. The recovery of diastolic blood pressure after TA was better than that of PA. When the tumor was 2 cm or small, TA had less blood loss than PA. There was no significant difference in functional indexes between PA and TA. PA offers advantages in surgical outcomes compared to TA. However, for tumors ≤2 cm, TA may provide greater benefits to patients. Additionally, TA demonstrates superior recovery of diastolic blood pressure compared to PA according to functional indicators.
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