ArticleRSC advances2025
Molecular interactions between surface-active ionic liquids based on 2-hydroxyethylammonium laurate with gabapentin: electrical conductivity and surface tension studies.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Effects of some surface active ionic liquids on the aqueous solubility, thermodynamic properties and fluorescence behavior of drug diclofenac sodium.Scientific reports · 2026Article
- The surface and micellar properties of ethanolamine based surface active ionic liquids in the presence of drug aspirin.Scientific reports · 2025Article
- Gabapentin drug interactions in water and aqueous solutions of green betaine based compounds through volumetric, viscometric and interfacial properties.Scientific reports · 2025Article
- Study of fluconazole drug behavior in deep eutectic solvents: thermodynamic properties, solubility measurement, and fluorescence spectroscopy.RSC advances · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Surface active ionic liquids (SAILs), offer potential advantages for pharmaceutical applications. Given the low permeability of gabapentin, an antiepileptic drug, in the gastrointestinal tract as classified by the Biopharmaceutics Classification Systems (BCS), understanding the micellization behavior of SAILs is essential for developing effective drug delivery systems to improve gabapentin bioavailability. This study explores the micellization and thermophysical behavior of SAILs (2-hydroxyethyl)ammonium laurate [2-HEA][Lau], bis(2-hydroxyethyl)ammonium laurate [BHEA][Lau], and tris(2-hydroxyethyl)ammonium laurate [THEA][Lau] in the presence of aqueous gabapentin solution at varied temperatures through COSMO analysis, electrical conductivity and surface tension measurements. The electrical conductivity and surface tension measurements were employed to obtain the critical micelle concentration (CMC) and related thermophysical properties of binary (SAILs + water) and ternary (SAILs + water + gabapentin) systems at (298.15 to 318.15) K such as Π (interface surface pressure),
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Registered trials
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