Evidence map›Paper›PMID 39822305›Full record

ArticleJournal of immunology research2025

NF-

Yael Schlichter Kadosh, Subramani Muthuraman, Ariel Kushmaro, Rajendran Saravana Kumar, Jacob Gopas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yael Schlichter KadoshAvram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben Gurion University of the Negev, Beer Sheva 84105, Israel.ORCID https://orcid.org/0009-0001-3389-8764
Subramani MuthuramanDepartment of Chemistry, Vellore Institute of Technology, Chennai Campus, Chennai 600127, Tamilnadu, India.
Ariel KushmaroAvram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben Gurion University of the Negev, Beer Sheva 84105, Israel.ORCID https://orcid.org/0000-0002-1970-9656
Rajendran Saravana KumarDepartment of Chemistry, Vellore Institute of Technology, Chennai Campus, Chennai 600127, Tamilnadu, India.ORCID https://orcid.org/0000-0002-7440-4038
Jacob GopasDepartment of Microbiology, Immunology and Genetics Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel.ORCID https://orcid.org/0000-0001-9289-8898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is a critical response of the immune system to infection or injury, serving to repair and restore tissue homeostasis. While acute inflammation generally protects against harmful stimuli, prolonged and chronic inflammation have detrimental effects and disrupts tissue homeostasis. Due to the complex and multifactorial etiology of chronic inflammation, effective treatment remains elusive. We found that piperlongumine (PL)-18, a di-hydroxy derivative of PL from long pepper, inhibits the nuclear factor kappa B (NF-

Indexed as

Anti-Inflammatory AgentsDioxolanesInflammationNF-kappa BA549 CellsCell LineCytokinesHumansI-kappa B KinasePiperidonesSignal TransductionTranscription Factor RelAAnti-Inflammatory AgentsCytokinesDioxolanesI-kappa B KinaseNF-kappa BPiperidonespiperlongumineTranscription Factor RelA

Identifiers

PMID39822305
PMCPMC11735059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.