Evidence map›Paper›PMID 39822293›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Incidence of dementia in the German Heinz Nixdorf Recall study over 20 years.

Sara Schramm, Charlotte Rinck, Nela Krizanovic, Karl-Heinz Jöckel, Anika Hüsing, Janine Gronewold, Dirk Hermann, Börge Schmidt, Andreas Stang, Martha Jokisch

Erratum issuedAbstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Sara SchrammFliedner University of Applied Sciences Düsseldorf Düsseldorf Germany.
Charlotte RinckInstitute for Medical Informatics Biometry and Epidemiology University Hospital Essen University Duisburg-Essen Essen Germany.
Nela KrizanovicInstitute for Medical Informatics Biometry and Epidemiology University Hospital Essen University Duisburg-Essen Essen Germany.
Karl-Heinz JöckelInstitute for Medical Informatics Biometry and Epidemiology University Hospital Essen University Duisburg-Essen Essen Germany.
Anika HüsingInstitute for Medical Informatics Biometry and Epidemiology University Hospital Essen University Duisburg-Essen Essen Germany.
Janine GronewoldDepartment of Neurology University Hospital Essen University Duisburg-Essen Essen Germany.
Dirk HermannDepartment of Neurology University Hospital Essen University Duisburg-Essen Essen Germany.
Börge SchmidtInstitute for Medical Informatics Biometry and Epidemiology University Hospital Essen University Duisburg-Essen Essen Germany.
Andreas StangInstitute for Medical Informatics Biometry and Epidemiology University Hospital Essen University Duisburg-Essen Essen Germany.
Martha JokischDepartment of Neurology University Hospital Essen University Duisburg-Essen Essen Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of the study was to estimate the population-based dementia incidence in Germany over a period of two decades.

methodsWe analyzed data from 4814 participants of the population-based Heinz Nixdorf Recall study (49.8% men, 45-75 years at baseline period 2000-2003), who have been monitored for the occurrence of cognitive decline and dementia. We calculated the cumulative incidence of dementia and its major subtypes and the incidence rate per 1000 person-years over two decades.

resultsDuring a median follow-up of 18.2 (Q1-Q3: 11.3-20.6) years, a total of 298 participants (6.2%) developed dementia (22.1% Alzheimer´s disease, 23.5% vascular dementia, 15.1% mixed dementia, 9.1% other dementia, 30.2% unspecified). The overall incidence rate was 3.9 per 1000 person-years. DISCUSSION: Our study is the only current population-based study in Germany that estimates the incidence of dementia. In order to reduce the high proportion of unspecific dementia diagnoses, diagnostics urgently need to be improved. Highlights: New data on the incidence of dementia in Germany in participants ≥45 years of age.Participants have been monitored for dementia incidence over two decades.The overall incidence in our cohort was 3.9 per 1000 person-years.Many patients had unspecific dementia diagnoses in their medical records.Further diagnostic evaluation should be available for all dementia patients.

Indexed as

Alzheimer´s diseasecohort studydementiaepidemiologyHeinz Nixdorf Recall studyincidenceincidence ratemixed dementiavascular dementia

Identifiers

PMID39822293
PMCPMC11736620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.