Evidence map›Paper›PMID 39822292›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Exploring the relationship between melanopsin gene variants, sleep, and markers of brain health.

Ayeisha Milligan Armstrong, Eleanor O'Brien, Tenielle Porter, Vincent Dore, Pierrick Bourgeat, Paul Maruff, Christopher C Rowe, Victor L Villemagne, Stephanie R Rainey-Smith, Simon M Laws and 1 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ayeisha Milligan ArmstrongCentre for Precision Health Edith Cowan University Joondalup Western Australia Australia.
Eleanor O'BrienCentre for Precision Health Edith Cowan University Joondalup Western Australia Australia.
Tenielle PorterCentre for Precision Health Edith Cowan University Joondalup Western Australia Australia.
Vincent DoreCentre for Precision Health Edith Cowan University Joondalup Western Australia Australia.
Pierrick BourgeatAustralian E-Health Research Centre CSIRO Herston Queensland Australia.
Paul MaruffAustralian E-Health Research Centre CSIRO Parkville Victoria Australia.
Christopher C RoweDepartment of Molecular Imaging and Therapy and Centre for PET Austin Health Heidelberg Victoria Australia.
Victor L VillemagneCentre for Precision Health Edith Cowan University Joondalup Western Australia Australia.
Stephanie R Rainey-SmithCentre for Healthy Ageing, Health Futures Institute Murdoch University Murdoch Western Australia Australia.
Simon M LawsCentre for Precision Health Edith Cowan University Joondalup Western Australia Australia.ORCID https://orcid.org/0000-0002-4355-7082
AIBL Research Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMelanopsin is a photopigment with roles in mediating sleep and circadian-related processes, which are often disrupted in Alzheimer's disease (AD). Melanopsin also impacts cognition and synaptogenesis. This study investigated the associations between melanopsin genetic variants, sleep, and markers of brain health.

methodsLinear regression analyses examined the relationship of single-nucleotide polymorphisms (SNPs) within the melanopsin gene (

resultsDISCUSSION: This study shows associations of Highlights: The relationships between melanopsin gene (

Indexed as

amyloidcognitionmelanopsinMRIsleep

Identifiers

PMID39822292
PMCPMC11736627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.