Evidence map›Paper›PMID 39822255›Full record

ArticleCureus2025

Skeletal Maturity Might Not Be a Factor in Optimizing Outcomes in Total Hip Arthroplasty.

Correggio L Peagler, Philip Parel, Kennedy Musgrave, Sarah Dance, Roxana Martinez, Savyasachi C Thakkar, Sean A Tabaie

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Correggio L PeaglerDepartment of Orthopaedic Surgery, George Washington University School of Medicine and Health Sciences, Washington, D.C., USA.
Philip ParelDepartment of Orthopaedic Surgery, George Washington University School of Medicine and Health Sciences, Washington, D.C., USA.
Kennedy MusgraveDepartment of Orthopaedic Surgery, George Washington University School of Medicine and Health Sciences, Washington, D.C., USA.
Sarah DanceDepartment of Orthopaedic Surgery, Children's National Hospital, Washington, D.C., USA.
Roxana MartinezDepartment of Orthopaedic Surgery, Case Western Reserve University Hospital, Cleveland, USA.
Savyasachi C ThakkarDepartment of Orthopaedic Surgery, Johns Hopkins Health System, Baltimore, USA.
Sean A TabaieDepartment of Orthopaedic Surgery, Nationwide Children's Hospital, Columbus, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Total hip arthroplasty (THA) is rarely indicated in the skeletally immature population. In these instances, there is concern for implant survival compared to the traditional older population. There has been a steady rise in the use of THA in the pediatric population due to improvements in surgical techniques. While the outcomes in THA for skeletally immature patients have been described in the literature, there are no population studies looking at this procedure in a skeletally immature individual. Therefore, the purpose of this study was to compare 10-year implant survivability following primary THA in skeletally mature versus skeletally immature patients. Methods Patients who underwent primary THA were identified using a large national database (PearlDiver). THA patients were then divided into presumed skeletally immature male patients (0-16 years), presumed skeletally mature male patients (17-21 years), presumed skeletally immature females (0-14 years), and presumed skeletally mature females (15-21 years). Multivariable analysis was conducted using Cox proportional hazards modeling to determine differences in the risk of revision for periprosthetic joint infection (PJI), mechanical loosening, dislocation/instability, and periprosthetic fracture (PPF). Results In total, 352 male patients (244 skeletally mature and 108 skeletally immature) and 409 female patients (350 skeletally mature and 59 skeletally immature) were identified. Compared to skeletally immature females, skeletally mature females had no higher risk of 10-year revision for all-cause, PJI, mechanical loosening, dislocation/instability, or PPF (P > 0.05 for all). Compared to skeletally immature males, skeletally mature males had no higher risk of 10-year revision for all-cause, PJI, mechanical loosening, dislocation/instability, or PPF (P > 0.05 for all). Conclusion Although THA occurred more commonly in patients above the presumed age of skeletal maturity, the lack of significantly different surgical outcomes suggests that younger age and presumed skeletal immaturity may not put patients at any further risk of implant failure. While further research is needed to understand the impact of age and skeletal maturity on outcomes of THA, these results indicate that the initial age of a THA may not be a factor in optimizing outcomes, and suggests that orthopedic surgeons need not delay surgery based on age or skeletal maturity alone.

Indexed as

pediatric orthopedic surgeryrevision joint replacementskeletal maturitytotal hip arthroplasty: thatotal hip replacement (thr)

Identifiers

PMID39822255
PMCPMC11736506

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.