Evidence map›Paper›PMID 39822196›Full record

ArticleArchives of rehabilitation research and clinical translation2024

Neurovisual Training With Acoustic Feedback: An Innovative Approach for Nystagmus Rehabilitation.

Damiano Antognetti, Luca Maggiani, Elena Gabbrielli, Luca Allegrini, Stefania Dalise, Carmelo Chisari

Abstract readCase Reports
In one paragraph

Article in Archives of rehabilitation research and clinical translation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Damiano AntognettiSection of Neurorehabilitation, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Luca MaggianiSection of Neurorehabilitation, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
Elena GabbrielliSection of Neurorehabilitation, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
Luca AllegriniSection of Ophthalmic Surgery, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
Stefania DaliseSection of Neurorehabilitation, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy.
Carmelo ChisariSection of Neurorehabilitation, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nystagmus has various clinical manifestations, including downbeat, upbeat, and torsional types, each associated with distinct neurologic features. Current rehabilitative interventions focusing on fixation training and optical correction often fail to achieve complete resolution. When nystagmus coexists with fragile X-associated tremor/ataxia syndrome (FXTAS), functional impairments worsen, particularly affecting balance. Recognizing these limitations, the authors propose an innovative approach using audiovisual stimulation to complement visual pursuit training and optical compensation, potentially improving rehabilitation outcomes. This study describes the case of a 60-year-old woman with worsening nystagmus and cerebellar ataxia suggestive of FXTAS who underwent a customized rehabilitation program. The program included 30 sessions involving audiovisual training and physical exercises. Visual performance assessments were conducted using AV-Desk and Nidek MP-1 microperimeters, with functional assessments including the Barthel Modified Index, 10-meter walking test, timed Up and Go, and Berg Balance Scale. After treatment, visual performance improved with reduced response times and higher success rates, especially without drugs. Fixation stability improved consistently using the bivariate contour ellipse area method. Functional assessments showed enhanced mobility and balance, with benefits sustained at the 6-month follow-up. The combined approach of audiovisual training, proprioceptive training, and targeted muscle strengthening has proven effective. Notable improvements in overall physical performance, especially in balance and gait, and a reduction in nystagmus severity were observed. Integrating audiovisual stimulation into rehabilitation protocols shows promising results in managing nystagmus and ataxia, significantly enhancing patients' quality of life. Further studies are needed to validate these findings and expand upon this approach.

Indexed as

AtaxiaAudiovisual trainingCase reportFXTASNystagmusRehabilitation

Identifiers

PMID39822196
PMCPMC11733972

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.