Evidence map›Paper›PMID 39821905›Full record

ArticleObesity surgery2025

Reversal of Roux-en-Y Gastric Bypass: A Multi-Centric Analysis of Indications, Techniques, and Surgical Outcomes.

Liane Plath, Marie Vannijvel, Sietske Okkema, Ellen Deleus, Aaron Lloyd, Emanuele Lo Menzo, George Tadros, Ivana Raguz, Andres San Martin, Marko Kraljević and 37 more

Abstract readMulticenter Study
In one paragraph

Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  8. Endoscopic ultrasound-assisted double-lumen-apposing metal stent septotomy for permanent partial reversal of Roux-en-Y gastric bypass.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

47 authors.

Liane PlathDepartment of Surgery, Männedorf Hospital, Männedorf, Switzerland.
Marie VannijvelDepartment of General Surgery, AZ Sint-Jan, Brugge, Belgium.
Sietske OkkemaDepartment of Surgery, Rijnstate Hospital, Arnhem, Netherlands.
Ellen DeleusDepartment of General Surgery, Universitair Ziekenhuis Leuven, Louvain, Belgium.
Aaron LloydMinimally Invasive and Bariatric Surgery, Fresno Heart and Surgical Hospital, Fresno, USA.
Emanuele Lo MenzoThe Bariatric and Metabolic Institute, Cleveland Clinic Florida, Weston, USA.
George TadrosThe Bariatric and Metabolic Institute, Cleveland Clinic Florida, Weston, USA.
Ivana RaguzDepartment of Surgery and Transplantation, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
Andres San MartinBariatric and Metabolic Center, Department of Surgery, Clínica Las Condes, Santiago, Chile.
Marko KraljevićDepartment of Visceral Surgery, Clarunis, Claraspital, Basel, Switzerland.
Styliani MantziariDepartment of Visceral Surgery, University Hospital of Lausanne, Lausanne, Switzerland.
Sebastien FreyDigestive Surgery and Liver Transplantation Unit, Centre Hospitalier Universitaire de Nice, Nice, France.
Lisa GensthalerDepartment of Surgery, Medical University of Vienna, Vienna, Austria.
Henna SammalkorpiDepartment of Surgery, Turku University Hospital, Turku, Finland.
José Luis García GalochaDepartment of Surgery, Hospital Clinico San Carlos, Complutense University of Madrid, Madrid, Spain.
Vaishnavi SujathanDepartment of Upper Gastrointestinal and Bariatric Surgery, St Richard's Hospital, University Hospitals Sussex NHS Foundation Trust, Chichester, UK.
Amalia ZapataBariatric and Metabolic Surgery Center, Hospital Dipreca, Santiago, Chile.
Talar TatarianDepartment of Surgery, Thomas Jefferson University Hospital, Philadelphia, USA.
Tom WigginsDepartment of Upper Gastrointestinal and Bariatric Surgery, Musgrove Park Hospital, Taunton, UK.
Ekhlas Samir BardisiDepartment of Surgery, Centre Hospitalier Universitaire de Saint-Pierre, Brussels, Belgium.
Jean-Philippe GoreuxDepartment of Surgery, Centre Hospitalier Universitaire de Saint-Pierre, Brussels, Belgium.
Yosuke SekiWeight Loss and Metabolic Surgery Center, Yotsuya Medical Cube, Tokyo, Japan.
Kazunori KasamaWeight Loss and Metabolic Surgery Center, Yotsuya Medical Cube, Tokyo, Japan.
Jacques HimpensDepartment of Surgery, Centre Hospitalier Universitaire de Saint-Pierre, Brussels, Belgium.
Marianne HollymanDepartment of Upper Gastrointestinal and Bariatric Surgery, Musgrove Park Hospital, Taunton, UK.
Richard WelbournDepartment of Upper Gastrointestinal and Bariatric Surgery, Musgrove Park Hospital, Taunton, UK.
Rajesh AggarwalDepartment of Surgery, Thomas Jefferson University Hospital, Philadelphia, USA.
Alec BeekleyDepartment of Surgery, Thomas Jefferson University Hospital, Philadelphia, USA.
Matias SepulvedaBariatric and Metabolic Surgery Center, Hospital Dipreca, Santiago, Chile.
Antonio TorresDepartment of Surgery, Hospital Clinico San Carlos, Complutense University of Madrid, Madrid, Spain.
Anne JuutiDepartment of Surgery, Turku University Hospital, Turku, Finland.
Paulina SalminenDepartment of Surgery, Turku University Hospital, Turku, Finland.
Gerhard PragerDepartment of Surgery, Medical University of Vienna, Vienna, Austria.
Antonio IannelliDigestive Surgery and Liver Transplantation Unit, Centre Hospitalier Universitaire de Nice, Nice, France.
Michel SuterDepartment of Visceral Surgery, University Hospital of Lausanne, Lausanne, Switzerland.
Ralph PeterliDepartment of Visceral Surgery, Clarunis, Claraspital, Basel, Switzerland.
Camilo BozaBariatric and Metabolic Center, Department of Surgery, Clínica Las Condes, Santiago, Chile.
Raul RosenthalThe Bariatric and Metabolic Institute, Cleveland Clinic Florida, Weston, USA.
Kelvin HigaMinimally Invasive and Bariatric Surgery, Fresno Heart and Surgical Hospital, Fresno, USA.
Matthias LannooDepartment of General Surgery, Universitair Ziekenhuis Leuven, Louvain, Belgium.
Eric HazebroekDepartment of Surgery, Rijnstate Hospital, Arnhem, Netherlands.
Christopher PringDepartment of Upper Gastrointestinal and Bariatric Surgery, St Richard's Hospital, University Hospitals Sussex NHS Foundation Trust, Chichester, UK.
Will HawkinsDepartment of Upper Gastrointestinal and Bariatric Surgery, St Richard's Hospital, University Hospitals Sussex NHS Foundation Trust, Chichester, UK.
Guy SlaterDepartment of Upper Gastrointestinal and Bariatric Surgery, St Richard's Hospital, University Hospitals Sussex NHS Foundation Trust, Chichester, UK.
Bruno DillemansDepartment of General Surgery, AZ Sint-Jan, Brugge, Belgium.
Marco Bueter *Department of Surgery, Männedorf Hospital, Männedorf, Switzerland.
Daniel Gero *Department of Surgery and Transplantation, University Hospital of Zurich, University of Zurich, Zurich, Switzerland. danielgero.md@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRoux-en-Y gastric bypass may present long-term complications that require revisional surgery or even reversal to normal anatomy. Data on the indications, surgical technique, and outcomes of RYGB reversal remain scarce.

methodsWe identified 48 cases of RYGB reversals with complete 90-day follow-up within a multi-centric international retrospective database of elective secondary bariatric surgery. The operations were performed between 2010 and 2024 in high-volume referral centers in Europe and USA. Data were collected on body weight, associated diseases, and on surgical outcomes up to 1-year postoperatively.

resultsPatients were mainly female (81.3%) with a median age of 50 years (IQR 39-56). RYGB reversal was performed 7 years (median) after primary RYGB in patients with a BMI of 23.9 kg/m

conclusionAlthough RYGB is a theoretically reversible procedure, normal anatomy is re-established only in selected cases which are refractory to medical therapy and often also to revisional bariatric surgery. RYGB reversals entail high morbidity, while the extent of recurrent weight gain at 1-year post-reversal seems to allow patients to remain below the threshold of severe obesity.

Indexed as

Gastric BypassObesity, MorbidPostoperative ComplicationsReoperationAdultBody Mass IndexEuropeFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeWeight LossAbdominal painComplicationsConversion to normal anatomyIndicationsMalnutritionOutcomesRecurrent weight gainReversalRoux-en-Y gastric bypassSecondary bariatric surgery

Identifiers

PMID39821905
PMCPMC11835901

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.