Evidence map›Paper›PMID 39821658›Full record

ReviewArchives of dermatological research2025

Research progress on quercetin in improving the survival rate of random skin flap.

Siping Xu, Wenhua Zhang, Xuanfen Zhang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Siping XuLanzhou University, Lanzhou, Gansu, 730000, China.
Wenhua ZhangOrthopedics Department, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, 353000, China.
Xuanfen ZhangDepartment of Plastic Surgery, the Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, Gansu, 730030, China. zhxf9304@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Random skin flap transplantation is critical in wound repair, organ reconstruction and cosmetic surgery, yet skin flap necrosis remains a common and challenging issue. Quercetin, a flavonoid abundant in various plants, exhibits anti-inflammatory, antioxidant, and other beneficial pharmacological effects. Recent studies suggest quercetin can improve random skin flap survival by modulating inflammation, reducing oxidative stress, and promoting angiogenesis. This review evaluates quercetin's potential mechanisms and efficacy, proposing a foundation for its clinical use in preventing ischemic necrosis and enhancing flap viability.

Indexed as

AntioxidantsGraft SurvivalQuercetinSkin TransplantationSurgical FlapsAnimalsAnti-Inflammatory AgentsHumansNecrosisOxidative StressSkinWound HealingAnti-Inflammatory AgentsAntioxidantsQuercetinFlap survivalIschemiaQuercetinRandom skin flapsTLR4/NF-κB

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.