ArticleThe British journal of radiology2025
Iodine concentration in the lung parenchyma in relation to different inspiratory depths during CT pulmonary angiography.
Article in The British journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Vascular attenuation and volumetric lung iodine density in dual-layer spectral CT pulmonary angiography: a randomized controlled trial comparing three contrast doses.European radiology · 2026Trial
- Article
- Bronchiectasis and airspace enlargement surrounding the lung nodule in dual-energy CT pulmonary angiography: comparison between iodine map and monochromatic image.Radiological physics and technology · 2025Article
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Abstract
objectivesThis study aimed to investigate the impact of changing inspiratory depth from end- to mid-inspiratory level on the iodine concentration in the lung parenchyma and main pulmonary artery in dual-energy CT pulmonary angiography.
methodsThis retrospective study included patients who underwent dual-energy CT pulmonary angiography from July 2020 to June 2023. Patients were instructed to hold their breath at end- and mid-inspiratory levels before and after January 2022, respectively. By placing regions of interest on the lung lobes and main pulmonary artery in the iodine map, their iodine concentration was recorded.
resultsIn end- and mid-inspiratory command, 173 (mean age: 63.4 ± 17.0 years; 68 males) and 179 (mean age: 65.1 ± 15.4 years; 62 males) patients, respectively, were included. The mean iodine concentrations of the right upper, right middle, right lower, left upper, and left lower lobes were 0.81/0.91, 0.67/0.74, 1.06/1.07, 0.85/0.95, and 1.07/1.11 mgI/mL, respectively, for the end-/mid-inspiratory level. The multivariable regression analysis revealed inspiratory depth as a significant factor for iodine concentration of the right upper, right middle, and left upper lobes. Main pulmonary artery iodine concentration in mid-inspiratory depth (13.21 mgI/mL) was higher than that in end-inspiratory depth (12.51 mgI/mL) (P = .129), and a statistically significant difference was observed in the patient group with a body weight of ≥70 kg (P = .015).
conclusionsChanging inspiratory depth from end- to mid-inspiratory level has a significant impact on the iodine concentration in the upper and right middle lobes in dual-energy CT pulmonary angiography. ADVANCES IN KNOWLEDGE: Changing inspiratory depth from end- to mid-inspiratory level has significantly increased the iodine concentration in the right upper, right middle, and left upper lobes.
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