Evidence map›Paper›PMID 39820868›Full record

ArticlePloS one2025

Deep learning-based skin lesion analysis using hybrid ResUNet++ and modified AlexNet-Random Forest for enhanced segmentation and classification.

Saleem Mustafa, Arfan Jaffar, Muhammad Rashid, Sheeraz Akram, Sohail Masood Bhatti

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

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8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Saleem MustafaFaculty of Computer Science & Information Technology, The Superior University, Lahore, Pakistan.
Arfan JaffarFaculty of Computer Science & Information Technology, The Superior University, Lahore, Pakistan.
Muhammad RashidDepartment of Computer Science, National University of Technology, Islamabad, Pakistan.
Sheeraz AkramFaculty of Computer Science & Information Technology, The Superior University, Lahore, Pakistan.ORCID 0000-0003-2321-3845
Sohail Masood BhattiFaculty of Computer Science & Information Technology, The Superior University, Lahore, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin cancer is considered globally as the most fatal disease. Most likely all the patients who received wrong diagnosis and low-quality treatment die early. Though if it is detected in the early stages the patient has fairly good chance and the aforementioned diseases can be cured. Consequently, diagnostic identification and management of the patient at this level becomes a rather enormous task. This paper offers a cutting-edge hybrid deep learning approach of better segmentation and classification of skin lesions. The proposed method incorporates three key stages: preprocessing, segmentation of lesions, and classification of lesions. By the stage of preprocessing, a morphology-based technique takes out hair so as to enhance the segmentation precision to use the cleansed images for subsequent analysis. Segmentation cuts off the lesion from the surrounding skin, giving the classification phase a dedicated area of interest and the ability to clear the background noise that may affect classification rates. The isolation enables the model to better analyze anatomical lesion features in order to achieve accurate benign and malignant classifications. Using ResUNet++, the cutting-edge deep learning architecture, we achieved accurate lesion segmentation. Next, we will modify and use an AlexNet-Random Forest (AlexNet-RF) based classifier for robust lesion classification. The proposed hybrid deep learning model is intensively validated on the Ham10000 data set which is one of the most popular datasets for skin lesions analysis. The obtained results show that the utilized approach, compared to the previous ones, is more effective, giving better segmentation and classification results. This method takes advantage of ResUNet++ strong classification skill and modified AlexNet-Random Forest robustness for more accurate segmentation. There is a high probability that ResUNet++, which is highly proficient at medical image segmentation, can produce better segmentation of lesions than the simpler models. The composition of AlexNet's extraction of features with Random Forest ability to reduce overfitting possibly may be more precise in the classification when compared to using only one model.

Indexed as

Convolutional Neural NetworksDeep LearningImage Processing, Computer-AssistedSkinSkin NeoplasmsAlgorithmsHumansRandom Forest

Identifiers

PMID39820868
PMCPMC11737724

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.