Evidence map›Paper›PMID 39820592›Full record

Trial reportPloS one2025

Tyrosine supplementation is ineffective in facilitating soccer players' physical and cognitive performance during high-intensity intermittent exercise in hot conditions.

Kate J Donnan, Emily L Williams, Nicholas Stanger

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kate J DonnanDepartment of Sport, Health and Exercise Science, University of Hull, Hull, United Kingdom.ORCID 0000-0003-4586-5465
Emily L WilliamsCarnegie School of Sport, Leeds Beckett University, Leeds, United Kingdom.
Nicholas StangerCarnegie School of Sport, Leeds Beckett University, Leeds, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tyrosine has been proposed to potentially provide ergogenic benefits to cognitive and physical performance in physiologically demanding environments. However research into its effectiveness on cognitive and physical performance during exercise in the heat has revealed mixed findings. This study examined the effects of a commonly employed dosage of tyrosine supplementation on soccer players' physical and decision-making performance, cognitive appraisal, and affective states, during prolonged high-intensity intermittent exercise in hot conditions. Eight trained male soccer players completed a 92-minute high-intensity intermittent cycling sprint protocol whilst responding to soccer-specific decision-making tasks at various time points in 32°C (50%rh), in two counterbalanced conditions; tyrosine (150mg.kg-1) and placebo. No differences were found for peak power output (p = .486; 715 ± 98W vs 724 ± 98W, respectively), decision-making (p = .627; 86.9 ± 10.7% vs 88.6 ± 7.0%, respectively), cognitive appraisal (p = .693, 0.90 ± 0.42 vs 0.88 ± 0.39, respectively) nor affective states (p = .918; 1.15 ± 1.55 vs 1.14 ± 1.70, respectively) between tyrosine and placebo conditions. Also, no condition by time interaction effects were noted for these outcomes. In sum, tyrosine supplementation was ineffective for facilitating prolonged intermittent sprint (self-paced) activity, soccer-specific decision-making, and in alleviating perceptual strain, for soccer players' exercising in the heat. However, future research may wish to consider alternative approaches for tyrosine supplementation (e.g., timing, dosage) or induce heightened physiological strain to extend on these findings.

Indexed as

Athletic PerformanceCognitionDietary SupplementsExerciseHot TemperatureSoccerTyrosineAdultDecision MakingHigh-Intensity Interval TrainingHumansMaleYoung AdultTyrosine

Identifiers

PMID39820592
PMCPMC11737745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.