Evidence map›Paper›PMID 39820519›Full record

ArticleScientific data2025

lncRNA, miRNA, and mRNA of plasma and tumor-derived exosomes of cardiac myxoma-related ischaemic stroke.

Lin Ma, Yu-Hua Liu, Chun Liu, Shu-Qi Wang, Jun Ma, Xiao-Qing Li, Min Ren, Ting-Ting Yang, Guang-Zhi Liu

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lin Ma *Department of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.ORCID http://orcid.org/0000-0001-5508-0456
Yu-Hua Liu *Department of Cardiosurgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Chun LiuDepartment of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Shu-Qi WangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610065, China.
Jun MaDepartment of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Xiao-Qing LiDepartment of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Min RenDepartment of Neurology, Shanghai Bluecross Brain Hospital, Shanghai, Beijing, China.
Ting-Ting YangDepartment of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China. ytt4705@163.com.
Guang-Zhi LiuDepartment of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China. liugz@mail.ccmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac myxoma (CM) is an important aetiology of stroke in young adults, and its diagnosis is difficult in patients having stroke because of the lack of diagnostic biomarkers. Tumour-derived exosomes play a crucial role in tumour growth, metastasis, immune regulation, and monitor disease development. Hence,we established an RNA-sequencing dataset for long non-coding RNA (lncRNA), microRNA (miRNA), and messenger RNA (mRNA) in the plasma and tumour-derived exosomes from four patients with cardiac myxoma-related ischaemic stroke (CM-IS) and six patients with cardiac myxoma without ischaemic stroke (non-IS CM). Moreover, 5,533 lncRNAs, 1,331 known miRNAs, and 412 new miRNAs were identified. Finally, gene expression profiles and differentially expressed genes were analysed in 20 samples. In the plasma samples, 74 miRNAs, 12 lncRNAs, and 693 mRNAs were identified, while tumour-derived tissue samples contained 61 miRNAs, 67 lncRNAs, and 433 mRNAs. This dataset provides a significant resource for relevant researchers to explore the potential dysregulated lncRNAs, miRNAs, and mRNAs of plasma and tumour-derived exosomes in CM-IS.

Indexed as

ExosomesHeart NeoplasmsIschemic StrokeMicroRNAsMyxomaRNA, Long NoncodingRNA, MessengerFemaleHumansMaleMicroRNAsRNA, Long NoncodingRNA, Messenger

Identifiers

PMID39820519
PMCPMC11739660

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.