Evidence map›Paper›PMID 39820514›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025

Longitudinal assessment of retinal and visual pathway electrophysiology and structure after high altitude exposure.

Xiaoling Shi, Minglu Li, Xinjuan Zhang, Fengjuan Yuan, Yanqiu Liu, Jianzhong Lin, Ran Zhang, Jia Liu, Xiaochuan Wang, Jiaxing Zhang

Abstract read
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaoling ShiXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, 361000, Fujian, China.
Minglu LiDepartment of Clinical Medicine, School of Medicine, Xiamen University, Xiamen, 361102, Fujian, China.
Xinjuan ZhangSchool of Education and Psychology, Minnan Normal University, Zhangzhou, 363000, China.
Fengjuan YuanInstitute of Brain Diseases and Cognition, School of Medicine, Xiamen University, Xiamen, 361102, Fujian, China.
Yanqiu LiuPhysical Education Institute, Jimei University, Xiamen, 361021, China.
Jianzhong LinMagnetic Resonance Center, Zhongshan Hospital Xiamen University, Xiamen, 361004, Fujian, China.
Ran ZhangInstitute of Brain Diseases and Cognition, School of Medicine, Xiamen University, Xiamen, 361102, Fujian, China.
Jia LiuDepartment of Anorectal Surgery, Xiamen Fifth Hospital, Xiamen, 361101, Fujian, China. jialiu1231@163.com.
Xiaochuan WangDepartment of Neurology, Affiliated Hospital of Hangzhou Normal University, Hangzhou, 310015, China. wangxc1226@163.com.
Jiaxing ZhangInstitute of Brain Diseases and Cognition, School of Medicine, Xiamen University, Xiamen, 361102, Fujian, China. zhangjiaxing@xmu.edu.cn.

Funding

Bureau of Science and Technology of Hangzhou 20201203B182National Natural Science Foundation of China 81871519 and 82171864Xiamen Natural Science Foundation 3502Z202374101
6 · The paper itself

Abstract

High altitude (HA) exposure induces impairments in visual function. This study was designed to dynamically observe visual function after returning to lowland and elucidate the underlying mechanism by examining the structure and function of retina and visual pathway. Twenty-three subjects were recruited before (Test 1), and one week (Test 2) and three months (Test 3) after their return from HA (4300 m) where they resided for 30 days. The clock task was used to assess visual cognition; and pattern-reversal visual evoked potential (p-VEP) and full-field electroretinogram (ff-ERG) were employed to record electrophysiological responses of retinal cells; optical coherence tomography (OCT), color doppler imaging (CDI) and magnetic resonance imaging(MRI) were used to measure structures of retina and visual pathway. In Test 2 vs. Test 1, there was increased reaction time during angle task; the amplitudes of scotopic 3.0 cd·s/m

Indexed as

AltitudeAltitude SicknessEvoked Potentials, VisualRetinaVisual AcuityVisual PathwaysAdultElectroretinographyFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleTomography, Optical CoherenceYoung AdultEyeFull-field electroretinogramHigh altitudeHypoxiaRetinaVisual evoked potential

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.