Evidence map›Paper›PMID 39820481›Full record

ArticleThe Journal of clinical endocrinology and metabolism2025

Multidimensional Sleep Health, Glycemic Control, and Self-reported Outcomes in Type 1 Diabetes: A Cross-sectional Study.

Ghada Abu Irsheed, Alana Steffen, Pamela Martyn-Nemeth, Minsun Park, Laurie Quinn, Jennifer Duffecy, Kelly Glazer Baron, Adam Hussain Saleh, Mary Takgbajouah, Olivia Bimbi and 3 more

Registry-linked trialAbstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04506151 (Sleep Optimization to Improve Glycemic Control in Adults With Type 1 Diabetes), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04506151 nacompletednot on this map

Sleep Optimization to Improve Glycemic Control in Adults With Type 1 Diabetes

TypeinterventionalSponsorUniversity of Illinois at ChicagoRan2021 to 2025Enrolled144ConditionsType 1 DiabetesArmsSleep-Opt, Healthy Living
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ghada Abu IrsheedCollege of Nursing, Department of Biobehavioral Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0002-5927-6285
Alana SteffenCollege of Nursing, Department of Population Health Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.
Pamela Martyn-NemethCollege of Nursing, Department of Biobehavioral Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0002-0323-3614
Minsun ParkCollege of Nursing, Department of Biobehavioral Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.
Laurie QuinnCollege of Nursing, Department of Biobehavioral Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.
Jennifer DuffecyDepartment of Psychiatry, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.
Kelly Glazer BaronDivision of Public Health, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT 84108, USA.
Adam Hussain SalehCollege of Nursing, Department of Biobehavioral Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.
Mary TakgbajouahCollege of Nursing, Department of Biobehavioral Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.
Olivia BimbiCollege of Nursing, Department of Biobehavioral Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.
Justine KesslerCollege of Nursing, Department of Biobehavioral Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.
Dan MihailescuDivision of Endocrinology, Cook County Health, Chicago, IL 60612, USA.
Sirimon ReutrakulCollege of Nursing, Department of Biobehavioral Nursing Science, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0002-0686-1069

Funding

Sleep optimization to improve glycemic control in adults with type 1 diabetesR01DK121726 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MARTYN-NEMETH, PAMELA ANN · 2020 to 2024
$3.0M
National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases R01DK121726).NIDDK NIH HHS R01 DK121726
6 · The paper itself

Abstract

contextSleep health is multidimensional. While studies have shown associations between certain sleep dimensions and health in type 1 diabetes (T1D), global sleep health has rarely been considered.

objectiveTo examine the associations between individual sleep dimensions and multidimensional sleep health (MSH) on glycemic control and self-reported outcomes in T1D.

methodsData from 116 adults with T1D participating in a sleep study (NCT04506151) were analyzed. Sleep satisfaction and alertness were assessed by questionnaires. Sleep timing, efficiency, duration, and regularity were derived from 7-day actigraphy. A composite MSH score was created by counting "healthy sleep" across these 6 measures. Glycemic control was assessed by 7-day continuous glucose monitoring and hemoglobin A1C (A1C). Self-reported outcomes were collected through questionnaires.

resultsAfter adjusting for covariates, greater sleep irregularity was associated with higher glycemic variability (b = 5.048, P < .01), less time in range (TIR) (b = -10.806, P < .01), higher time above range (TAR) (b = 7.40, P < .05), and higher A1C (b = .365, P < .05)]. Poor sleep satisfaction was associated with higher diabetes distress and depression (b = .29, P < .05, b = 3.59, P < .05), respectively. Later sleep timing was associated with higher depression (b = 1.545, P < .05), while lower sleep efficiency was associated with higher depression (b = 1.545, P < .01). Worse MSH was significantly associated with lower TIR (b = 2.376, P < .05), higher TAR, higher A1C, and depression (b = -2.38, P < .05; b = -.177, P < .01; b = -1.275, P < .05, respectively).

conclusionSleep irregularity likely drives the association between MSH and glycemic control, while poor sleep satisfaction, lower efficiency, and later timing contribute to the association between MSH and depression. These results highlight the importance of comprehensive sleep health evaluation in T1D.

Indexed as

Diabetes Mellitus, Type 1Glycemic ControlSleepSleep QualitySleep Wake DisordersAdultBlood GlucoseBlood Glucose Self-MonitoringCross-Sectional StudiesFemaleGlycated HemoglobinHumansMaleMiddle AgedRandomized Controlled Trials as TopicSelf ReportBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humandiabetes self-managementglycemic statusglycemic variabilitymultidimensional sleep healthpsychological healthtype 1 diabetes

Identifiers

PMID39820481
PMCPMC12680427

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.