Evidence map›Paper›PMID 39820479›Full record

ArticleSleep2025

Sleep trajectory of hospitalized medically ill older adults: do sleep medications make a difference?

Juliana Smichenko, Tamar Shochat, Anna Zisberg

Abstract readMulticenter Study
In one paragraph

Article in Sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Juliana SmichenkoThe Cheryl Spencer Department of Nursing and the Cheryl Spencer Institute of Nursing Research, Faculty of Social Welfare and Health Science, University of Haifa, Haifa, Israel.ORCID 0000-0002-2855-0210
Tamar ShochatThe Cheryl Spencer Department of Nursing and the Cheryl Spencer Institute of Nursing Research, Faculty of Social Welfare and Health Science, University of Haifa, Haifa, Israel.ORCID 0000-0002-4371-3567
Anna ZisbergThe Cheryl Spencer Department of Nursing and the Cheryl Spencer Institute of Nursing Research, Faculty of Social Welfare and Health Science, University of Haifa, Haifa, Israel.ORCID 0000-0002-8234-5218

Funding

Israeli Science Foundation 1216/17
6 · The paper itself

Abstract

STUDY

objectivesSleep disturbances are prevalent during acute hospitalization in medically ill older patients, with undesirable outcomes. Sleep medication use is common, but its effectiveness is questionable. This study explored the trajectory of sleep parameters from home to hospital and assessed the impact of sleep medication use, considering covariates such as physical symptom burden.

methodsA prospective multicenter study was conducted in four Israeli hospitals. Cognitively intact older patients (n = 683), with an admission interview and at least one follow-up, were recruited. Total sleep time (TST), sleep efficiency (SE), sleep quality (SQ), number of awakenings (NOAs), sleep medication use, sleep medication burden (quantity and dosage), and physical symptom burden were recorded daily. Personal and illness-related covariates were included in a repeated measures mixed models design.

resultsParticipants (male: 54%, aged 77.31 ± 6.60) showed shorter TST (329.73 ± 111.94 vs. 377.03 ± 101.06 min), lower SE (71.49 ± 19.28% vs. 76.14 ± 15.53%), and higher probability for lower SQ, in the hospital compared to home. Sleep medication use was not correlated with any sleep parameters; sleep medication burden was associated with NOA. Physical symptom burden showed significant main effects on SE, SQ, and NOA, and a significant interaction was found with time points on TST, such that higher burden was more strongly associated with shorter TST at first in-hospital follow-up than at admission, with no differences between all subsequent in-hospital time points.

conclusionsSleep declined during acute hospitalization compared to the home, with sleep medications showing minimal effect. Managing symptom burden should be prioritized when addressing sleep disturbances in older patients during hospitalization.

Indexed as

HospitalizationHypnotics and SedativesSleepSleep Wake DisordersAgedAged, 80 and overFemaleHumansIsraelMaleProspective StudiesSleep QualityHypnotics and Sedativeshospitalmedical unitolder adultssleep medicationssymptoms

Identifiers

PMID39820479
PMCPMC12257930

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.