ArticleNature communications2025
Rational engineering of DNA-nanoparticle motor with high speed and processivity comparable to motor proteins.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Assembly-Energetics-Control (AEC) Design Framework for Rotary DNA Nanomachines.Chembiochem : a European journal of chemical biology · 2026Review
- Programming DNA machines to move.Nature reviews. Chemistry · 2026Review
- A tunable autonomous RNA-fueled micro-engine.Nature communications · 2026Article
- DNA Motors Powered by Exonuclease III for Autonomous Rolling Motion and Biosensing Applications.bioRxiv : the preprint server for biology · 2025Article
- On-Demand Photoactivation of DNA-Based Motor Motion.ACS nano · 2025Article
- Rational engineering of DNA-nanoparticle motor with high speed and processivity comparable to motor proteins.Nature communications · 2025Article
- Approaching active matter from biophysics perspective.Biophysics and physicobiology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
DNA-nanoparticle motor is a burnt-bridge Brownian ratchet moving on RNA-modified surface driven by Ribonuclease H (RNase H), and one of the fastest nanoscale artificial motors. However, its speed is still much lower than those of motor proteins. Here we resolve elementary processes of motion and reveal long pauses caused by slow RNase H binding are the bottleneck. As RNase H concentration ([RNase H]) increases, pause lengths shorten from ~70 s to ~0.2 s, while step sizes (displacements between two consecutive pauses) are constant ( ~ 20 nm). At high [RNase H], speed reaches ~100 nm s
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.