ArticleMicrosystems & nanoengineering2025
Optofluidic paper-based analytical device for discriminative detection of organic substances via digital color coding.
Article in Microsystems & nanoengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Wearable Electronics for Precision Diagnosis Through Advanced Manufacturing and Integration.Nano-micro letters · 2026Review
- Review of Recent Optofluidic Devices.Micromachines · 2026Article
- Paper-Based Microfluidic Devices: A Powerful Strategy for Rapid Detection.Micromachines · 2025Review
- Miniaturization of Ocean Sensors Based on Optofluidic Technology: A Review.Sensors (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Developing a portable yet affordable method for the discrimination of chemical substances with good sensitivity and selectivity is essential for on-site visual detection of unknown substances. Herein, we propose an optofluidic paper-based analytical device (PAD) that consists of a macromolecule-driven flow (MDF) gate and photonic crystal (PhC) coding units, enabling portable and scalable detection and discrimination of various organic chemical, mimicking the olfactory system. The MDF gate is designed for precise flow control of liquid analytes, which depends on intermolecular interactions between the polymer at the MDF gate and the liquid analytes. Subsequently, the PhC coding unit allows for visualizing the result obtained from the MDF gate and generating differential optical patterns. We fabricate an optofluidic PAD by integrating two coding units into a three-dimensional (3D) microfluidic paper within a 3D-printed cartridge. The optofluidic PADs clearly distinguish 11 organic chemicals with digital readout of pattern recognition from colorimetric signals. We believe that our optofluidic coding strategy mimicking the olfactory system opens up a wide range of potential applications in colorimetric monitoring of chemicals observed in environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.