Evidence map›Paper›PMID 39819933›Full record

ArticleBMJ open2025

Patient preferences for drug therapy in inflammatory arthritis: protocol for a living systematic review and evidence map to inform clinical practice guidelines.

Pakeezah Saadat, Nick Bansback, Marie Falahee, Mickaël Hiligsmann, Peter Tugwell, Rachelle Buchbinder, Samuel Whittle, Dawn P Richards, Laurie Proulx, Holger Schunemann and 6 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Pakeezah SaadatInstitute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-5902-8962
Nick BansbackSchool of Population and Public Health, The University of British Columbia, Vancouver, British Columbia, Canada.
Marie FalaheeRheumatology Research Group, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.ORCID http://orcid.org/0000-0001-5928-486X
Mickaël HiligsmannDepartment of Health Services Research, CAPHRI Care and Public Health research Institute, Maastricht University, Maastricht, Netherlands.ORCID http://orcid.org/0000-0003-4274-9258
Peter TugwellDepartment of Medicine, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada.
Rachelle BuchbinderMusculoskeletal Health and Wiser Health Care Units, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Samuel WhittleSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Dawn P RichardsCanadian Arthritis Patient Alliance, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-1151-0826
Laurie ProulxCanadian Arthritis Patient Alliance, Toronto, Ontario, Canada.
Holger SchunemannDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Pablo Alonso-CoelloCentro GRADE Barcelona, Instituto de Investigacion Biomedica, Barcelona, Spain.ORCID http://orcid.org/0000-0002-8001-8504
Robby NieuwlaatDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Wojtek WierciochDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Simon KuperFaculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Limburg, Netherlands.
Jordi Pardo PardoCochrane Musculoskeletal, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Glen HazlewoodArthritis Research Canada, Richmond, British Columbia, Canada gshazlew@ucalgary.ca.ORCID http://orcid.org/0000-0001-7709-3741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe pharmacological management of inflammatory arthritis often requires choices that involve trade-offs between benefits, risks and other attributes such as administration route, frequency and cost. This living systematic review aims to inform international clinical guidelines on inflammatory arthritis by creating an evidence map of patient preference studies concerning the trade-offs in pharmacological management of inflammatory arthritis. METHODS AND ANALYSIS: We will include published and peer-reviewed full-text studies in any language that quantitatively assess preferences of patients for the pharmacological management of inflammatory arthritis (rheumatoid arthritis, spondyloarthritis and juvenile idiopathic arthritis). Studies must use either stated or revealed preference methods to assess preferences and provide a quantitative assessment of relevant characteristics, such as benefits, risks, costs and process attributes. Articles will identified through Medline and EMBASE database searches from inception using search terms that combine keywords and subject headings for inflammatory arthritis and preference-based methods, and a search in the Health Preference Study and Technology Registry using keywords for the populations of interest. Two independent reviewers will perform abstract and full-text screening. Risk of bias will be assessed using the GRADE risk of bias tool. An evidence map will be generated to summarise included studies and their assessments of each trade-off. The search will be conducted every 6 months with new studies added to the inventory. ETHICS AND DISSEMINATION: Ethics approval is not required. Results from the base review will be published in a peer-reviewed journal and findings will be presented at conferences. In the living model, we will publish updates and datasets on an Open Science Framework page, with periodic updates in peer-reviewed journals.

Indexed as

Antirheumatic AgentsArthritis, JuvenileArthritis, RheumatoidPatient PreferenceHumansPractice Guidelines as TopicResearch DesignSystematic Reviews as TopicAntirheumatic AgentsPatientsRHEUMATOLOGYSystematic Review

Identifiers

PMID39819933
PMCPMC11751828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.