Trial reportCritical care (London, England)2025
Distribution of airway pressure opening in the lungs measured with electrical impedance tomography (POET): a prospective physiological study.
Trial report in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05825534 (Pressure Opening With Electrical Impedance Tomography), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pressure Opening With Electrical Impedance Tomography
Who cites it
5 citing papers in PubMed.
- EIT in ARDS: what we know and what we still do not.Intensive care medicine · 2026Article
- ARDS management beyond the guidelines: a practical physiology-based approach to individualized care.Intensive care medicine · 2026Review
- Recent advances in experimental and clinical applications of chest electrical impedance tomography: a narrative review.Intensive care medicine experimental · 2026Review
- Airway opening pressure in mechanically ventilated patients: regional distribution and impact of body position.Critical care (London, England) · 2025Article
- Computer model-based injury prediction and evaluation of lung function in mice with acute and ventilator-induced lung injuries.American journal of physiology. Lung cellular and molecular physiology · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundIn patients with acute hypoxemic respiratory failure (AHRF) under mechanical ventilation, the change in pressure slope during a low-flow insufflation indicates a global airway opening pressure (AOP) needed to reopen closed airways and may be used for titration of positive end-expiratory pressure.
objectivesTo understand 1) if airways open homogeneously inside the lungs or significant regional AOP variations exist; 2) whether the pattern of the pressure slope change during low-flow insufflation can indicate the presence of regional AOP variations.
methodsUsing electrical impedance tomography, we recorded low-flow insufflation maneuvers (< 10 L/min) starting from end-expiratory positive pressure 0-5 cmH
resultsAmong the 36 patients analyzed, 9 (25%) had AOP
conclusionAOP
trial registrationClinicaltrials.gov, NCT05825534 (registered, April 24th, 2023), retrospectively registered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.