Evidence map›Paper›PMID 39819719›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2025

Wenjuan Duo, Yixiang Wang, Jiaxing Wang, Xinlong Xu, Linxian Li, Dongchen Yang, Qili Shen, Lichun Yang, Xiaojing Liu, Qiwang Jing and 2 more

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wenjuan DuoSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu 233030, China.
Yixiang WangSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu 233030, China.
Jiaxing WangSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu 233030, China.
Xinlong XuSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu 233030, China.
Linxian LiSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu 233030, China.
Dongchen YangSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu 233030, China.
Qili ShenDepartment of General Surgery, Second Affiliated Hospital of Bengbu Medical University, Bengbu 233030, China.
Lichun YangDepartment of General Surgery, Second Affiliated Hospital of Bengbu Medical University, Bengbu 233030, China.
Xiaojing LiuSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu 233030, China.
Qiwang JingSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu 233030, China.
Liang ChuDepartment of General Surgery, Second Affiliated Hospital of Bengbu Medical University, Bengbu 233030, China.
Xiaodi YangSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu 233030, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the protective effect of

methodsSixty male C57BL/6 mice randomized equally into sham-operated group, protein group, "two-hit" modeling group, and protein intervention group. In the former two groups, the mice received an intraperitoneal injection of 100 μL PBS followed by exposure of the cecum and then by intraperitoneal injection of 100 μL PBS or 25 μg r

resultsThe 72-h survival rates in the 4 groups were 100%, 100%, 0% and 20%, respectively, showing significant differences between the latter two groups. The mouse models of "two-hit" sepsis exhibited obvious tissue pathologies and significant elevations of TNF-α and IL-6 in both the serum and tissue homogenate, which were significantly ameliorated by r

conclusionsr

Indexed as

CystatinsSchistosoma japonicumSepsisAnimalsDisease Models, AnimalInterleukin-10Interleukin-6MaleMiceMice, Inbred C57BLTransforming Growth Factor betaTumor Necrosis Factor-alphaCystatinsInterleukin-10Interleukin-6Transforming Growth Factor betaTumor Necrosis Factor-alphacecal ligation and punctureimmunoregulatory cytokineslipopolysaccharideSchistosoma japonicum cysteine protease inhibitorssepsis

Identifiers

PMID39819719
PMCPMC11744279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.