Evidence map›Paper›PMID 39819528›Full record

ReviewCurrent pharmaceutical biotechnology2026

Lutein and Zeaxanthin: Source, Extraction, Stability, Bioactivity, and Functional Food Applications.

Surabhi Pandey, Akansha Gupta, Dipendra Kumar Mahato, Veena Paul, Abhishek Dutt Tripathi, Prasad Rasane, Pradeep Kumar, Madhu Kamle, Shafiul Haque

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pharmaceutical biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Effects ofBiology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Surabhi PandeyDepartment of Food Technology, Harcourt Butler Technical University, Kanpur, 208002, India.
Akansha GuptaCASS Food Research Centre, School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC 3125, Geelong, Australia.
Dipendra Kumar MahatoCASS Food Research Centre, School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC 3125, Geelong, Australia.
Veena PaulDivision of Food Processing Technology, School of Engineering and Technology, Karunya Institute of Technology and Sciences, Coimbatore-641114, India.
Abhishek Dutt TripathiDepartment of Dairy Science and Food Technology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi, 221005, India.
Prasad RasaneDepartment of Food Technology and Nutrition, School of Agriculture, Lovely Professional University, Phagwara, 144411, India.
Pradeep KumarDepartment of Botany, University of Lucknow, Lucknow, 226007, India.
Madhu KamleDepartment of Biochemistry, University of Lucknow, Lucknow-226007, India.
Shafiul HaqueResearch & Scientific Studies Unit, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.

Funding

Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia ISP23-101
6 · The paper itself

Abstract

Nature has been acknowledged as a fundamental source of diverse bioactive molecules. Among natural carotenoids, lutein, zeaxanthin, and their oxidative metabolites are specifically deposited in the macular region of living organisms. Lutein and zeaxanthin are carotenoids primarily found in green leafy vegetables, eggs, and various fruits. Lutein and zeaxanthin emerge as the primary carotenoids in the retina, playing a crucial role as photo-protectants to prevent retinal degeneration. The extraction of lutein and zeaxanthin from natural sources involves several techniques, including solvent extraction and supercritical fluid extraction, with an emphasis on optimizing efficiency and yield. Incorporating these carotenoids into functional foods-such as fortified dairy products, baked goods, and snacks-enhances their nutritional profiles and provides significant health benefits. This review examines the sources, stability, bioactivity, and various extraction methods for lutein and zeaxanthin, highlighting their potential for photoprotection, antioxidant activity, and antidiabetic effects. These attributes, combined with innovative extraction techniques, position lutein and zeaxanthin as promising ingredients for functional food applications.

Indexed as

Functional FoodLuteinZeaxanthinsAnimalsAntioxidantsHumansAntioxidantsLuteinZeaxanthinsantioxidantcarotenoidsfood applicationsLuteinmacular degenerationzeaxanthin

Identifiers

PMID39819528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.