Evidence map›Paper›PMID 39819251›Full record

Trial reportHuman vaccines & immunotherapeutics2025

Immunogenicity persistence after four intramuscular triple-dose or standard-dose hepatitis B vaccine in patients receiving methadone maintenance treatment: A 1-year follow-up study in China.

Xinyuan Mo, Zhaoyue Men, Linying Gao, Yizhuo Gao, Tian Yao, Yuan Liu, Yuan Yuan, Tongchuan Xue, Fuzhen Wang, Suping Wang and 3 more

Registry-linked trialAbstract readClinical Trial, Phase IVRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03962816 (A Prospective Study on the Immunogenicity and Persistence of Hepatitis B Vaccine in Methadone Maintenance Treatment Patients), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03962816 phase4unknown statusnot on this map

A Prospective Study on the Immunogenicity and Persistence of Hepatitis B Vaccine in Methadone Maintenance Treatment Patients

TypeinterventionalSponsorShanxi Medical UniversityRan2019 to 2023Enrolled300ConditionsHepatitis B VaccineArms20 µg recombinant hepatitis B vaccine at months 0, 1, and 6, 20 µg recombinant hepatitis B vaccine at months 0, 1, 2, and 6, 60 µg recombinant hepatitis B vaccine at months 0, 1, 2, and 6
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xinyuan MoSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Zhaoyue MenSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Linying GaoSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Yizhuo GaoSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Tian YaoCenter of Clinical Epidemiology and Evidence Based Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Yuan LiuMethadone Maintenance Treatment Clinic, Compulsory Isolation Drug Rehabilitation Center, Taiyuan, Shanxi, China.
Yuan YuanMethadone Maintenance Treatment Clinic, 109 hospital, Taiyuan, Shanxi, China.
Tongchuan XueXinghualing District Methadone Maintenance Treatment Clinic, Taiyuan, Shanxi, China.
Fuzhen WangChinese Center for Disease Control and Prevention, Beijing, China.
Suping WangSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.
Keke WangFirst Hospital/First Clinical Medical College, Shanxi Medical University, Taiyuan, Shanxi, China.
Xiaofeng LiangInstitute of Vaccine Industry, Institute of Disease Control and Prevention, Jinan University, Guangzhou, Guangdong, China.
Yongliang FengSchool of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CLINICAL

trial registrationClinicalTrials.gov (NCT03962816).https://clinicaltrials.gov/ct2/show/NCT03962816.

Indexed as

Hepatitis BHepatitis B AntibodiesHepatitis B VaccinesImmunogenicity, VaccineMethadoneOpiate Substitution TreatmentAdultChinaFemaleFollow-Up StudiesHumansInjections, IntramuscularMaleMiddle AgedYoung AdultHepatitis B AntibodiesHepatitis B VaccinesMethadonehepatitis B vaccinationmethadone maintenance treatmentparallel-controlled trialPersistence of immunogenicityrandomized controlled trial

Identifiers

PMID39819251
PMCPMC12934167

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.