Evidence map›Paper›PMID 39818920›Full record

ArticleDevelopmental psychology2025

Pubertal timing as a predictor of epigenetic aging and mortality risk in young adulthood.

Marlon Goering, Malcolm Barker-Kamps, Amit Patki, Hemant K Tiwari, Sylvie Mrug

Abstract read
In one paragraph

Article in Developmental psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marlon GoeringDepartment of Psychology, University of Alabama at Birmingham.ORCID 0000-0001-6708-6513
Malcolm Barker-KampsDepartment of Psychology, University of Alabama at Birmingham.
Amit PatkiDepartment of Biostatistics, University of Alabama at Birmingham.
Hemant K TiwariDepartment of Biostatistics, University of Alabama at Birmingham.
Sylvie MrugDepartment of Psychology, University of Alabama at Birmingham.

Funding

Project 2: Leveraging Ongoing Home Visitation Programs to Address Obesity Disparities among Underserved, Low-Income Mothers and ChildrenU54MD000502 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SALVY, SARAH-JEANNE · 2017 to 2022
$11.8M
Neurobiological Mechanisms of Lower Internalizing Disorders in Black AmericansR01MH098348 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KNIGHT, DAVID C, MRUG, SYLVIE · 2012 to 2016
$2.9M
Early Life Stress, DNA Methylation, and Health Disparities across AgesR01MD016044 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MRUG, SYLVIE · 2021 to 2025
$2.8M
Gender and Ethnicity in Early Substance Use InitiationK01DA024700 · NIDA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MRUG, SYLVIE · 2008 to 2011
$575k
CDC HHSFoundation for the National Institutes of HealthNIDA NIH HHS K01 DA024700NIMHD NIH HHS R01 MD016044NIMHD NIH HHS U54 MD000502NIMH NIH HHS R01 MH098348
6 · The paper itself

Abstract

Early pubertal timing is associated with adverse health in adulthood. These effects may be mediated by DNA methylation changes associated with accelerated cellular aging and mortality risk, but few studies tested associations between pubertal timing and epigenetic markers in adulthood. Additionally, pubertal timing effects often vary by sex and are understudied in diverse youth. Thus, this longitudinal study examined links between pubertal timing and later epigenetic aging and mortality risk together with sex differences in predominantly Black youth. Participants included 350 individuals (58% female, 42% male; 80% Black, 19% non-Hispanic White). Perceived pubertal timing relative to peers and self-reported phenotypic pubertal timing based on age-adjusted Tanner scores were assessed during early adolescence (

Indexed as

AgingEpigenesis, GeneticMortalityPubertyAdolescentAdultBlack or African AmericanFemaleHumansLongitudinal StudiesMaleWhiteYoung Adult

Identifiers

PMID39818920
PMCPMC12021574

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.