Evidence map›Paper›PMID 39818791›Full record

ArticleAnalytical chemistry2025

Your Blood is Out for Delivery: Considerations of Shipping Time and Temperature on Degradation of RNA from Stabilized Whole Blood.

Filip Stefanovic, Lauren G Brown, James MacDonald, Theo Bammler, Darawan Rinchai, Serena Nguyen, Yuting Zeng, Victoria Shinkawa, Karen Adams, Damien Chaussabel and 3 more

Abstract read
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Filip StefanovicDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Lauren G BrownDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-5932-2691
James MacDonaldDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, United States.
Theo BammlerDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, United States.
Darawan RinchaiDepartment of Infectious Diseases, St Jude's Children Research Hospital, Tennessee, Memphis 38105, United States.
Serena NguyenDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Yuting ZengDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Victoria ShinkawaDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Karen AdamsDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Damien ChaussabelComputer Sciences Department, The Jackson Laboratory, Farmington, Connecticut 06032, United States.
Erwin BerthierDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-4421-9034
Amanda J HaackDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Ashleigh B ThebergeDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-3394-1435

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI ALI SHOJAIE · 1995 to 2026
$42.5M
Theberge Admin Supp Undergraduate Summer Research ExperiencesR35GM128648 · NIGMS · UNIVERSITY OF WASHINGTON · PI Ashleigh Brooks Theberge · 2018 to 2026
$4.7M
Assessing the interplay between stress, health, behavior, and inflammatory gene expression response to wildfire smoke exposures using community engaged and remote sampling approaches - Brown Div SuppR21ES034338 · NIEHS · UNIVERSITY OF WASHINGTON · PI ERRETT, NICOLE ANN, THEBERGE, ASHLEIGH BROOKS · 2022 to 2023
$544k
NIEHS NIH HHS P30 ES007033NIEHS NIH HHS R21 ES034338NIGMS NIH HHS R35 GM128648
6 · The paper itself

Abstract

Remote research studies are an invaluable tool for reaching populations with limited access to large medical centers or universities. To expand the remote study toolkit, we previously developed homeRNA, which allows for at-home self-collection and stabilization of blood and demonstrated the feasibility of using homeRNA in high temperature climates. Here, we expand upon this work through a systematic study exploring the effects of high temperature on RNA integrity (represented as RNA Integrity Number, RIN) through in-lab and field experiments. Compared to the frozen controls (overall mean RIN of 8.2,

Indexed as

BloodRNARNA StabilityTemperatureTransportationHumansPrincipal Component AnalysisSequence Analysis, RNATime FactorsUnited StatesRNA

Identifiers

PMID39818791
PMCPMC12036334

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.