ArticleJournal of the American Chemical Society2025
Manganese(I)-Catalyzed Enantioselective Alkylation To Access P-Stereogenic Phosphines.
Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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Who cites it
3 citing papers in PubMed.
- Article
- Catalyst-Controlled Regio- and Enantioselective Hydrophosphination of α,β-Unsaturated Pyridyl Ketones.ACS omega · 2026Article
- P-Chiral Organophosphorus Compounds: Synthesis, Mechanism, and Applications.Chemistry, an Asian journal · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
This work introduces a novel Mn(I)-catalyzed enantioselective alkylation methodology that efficiently produces a wide array of P-chiral phosphines with outstanding yields and enantioselectivities. Notably, the exceptional reactivity of Mn(I) complexes in these reactions is demonstrated by their effective catalysis with both typically reactive alkyl iodides and bromides, as well as with less reactive alkyl chlorides. This approach broadens the accessibility to various P-chiral phosphines and simplifies the synthesis of chiral tridentate pincer phosphines to a concise 1-2 step process, contrary to conventional, labor-intensive multistep procedures. Importantly, the development significantly expands the applicability of earth-abundant Mn(I)-based complexes beyond their recently established roles in catalytic hydrogenative and conjugate addition reactions, emphasizing the catalytic potential of Mn(I) complexes as a viable alternative to noble metal chemistry and, in some cases, even surpassing their performance.
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Registered trials
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