Evidence map›Paper›PMID 39818019›Full record

ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2025

Spatially constrained hyperpolarized 13C MRI pharmacokinetic rate constant map estimation using a digital brain phantom and a U-Net.

Sule Sahin, Anna Bennett Haller, Jeremy Gordon, Yaewon Kim, Jasmine Hu, Tanner Nickles, Qing Dai, Andrew P Leynes, Daniel B Vigneron, Zhen Jane Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sule SahinUC Berkeley - UCSF Graduate Program in Bioengineering, 1700 4th St, San Francisco, CA 94158, USA; Radiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA. Electronic address: sisahin8@gmail.com.
Anna Bennett HallerUC Berkeley - UCSF Graduate Program in Bioengineering, 1700 4th St, San Francisco, CA 94158, USA; Radiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA.
Jeremy GordonRadiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA.
Yaewon KimRadiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA.
Jasmine HuRadiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA.
Tanner NicklesUC Berkeley - UCSF Graduate Program in Bioengineering, 1700 4th St, San Francisco, CA 94158, USA; Radiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA.
Qing DaiRadiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA; Radiological Sciences, University of California, Los Angeles, 300 UCLA Medical Plaza, Los Angeles, CA 90095, USA.
Andrew P LeynesRadiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA.
Daniel B VigneronUC Berkeley - UCSF Graduate Program in Bioengineering, 1700 4th St, San Francisco, CA 94158, USA; Radiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA.
Zhen Jane WangRadiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA.
Peder E Z LarsonUC Berkeley - UCSF Graduate Program in Bioengineering, 1700 4th St, San Francisco, CA 94158, USA; Radiology and Biomedical Imaging, University of California, San Francisco, 1700 4th St, San Francisco, CA 94158, USA.

Funding

TR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Daniel B Vigneron · 2011 to 2026
$19.9M
Translating Hyperpolarized 13C Metabolic MRI to Predict Renal Tumor AggressivenessR01CA249909 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LARSON, PEDER ERIC ZUFALL, WANG, ZHEN JANE · 2021 to 2025
$3.2M
Hyperpolarized 13C MRI of Cardiac Metabolic Remodeling in Heart DiseaseR01HL171992 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Maria Roselle Abraham, Peder Eric Zufall Larson · 2024 to 2026
$2.4M
Upgrade of an Obsolete 3.35T DNP Polarizer to enable new HP C-13 Technology DevelopmentS10OD025077 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VIGNERON, DANIEL B · 2020 to 2020
$1.7M
Hyperpolarized Carbon-13 Metabolic MRI of the Human HeartR33HL161816 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ABRAHAM, MARIA ROSELLE, LARSON, PEDER ERIC ZUFALL · 2022 to 2023
$965k
Hyperpolarized 13C Metabolic MRI for Noninvasive Monitoring of Kidney InjuryR21DK130002 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LARSON, PEDER ERIC ZUFALL, WANG, ZHEN JANE · 2021 to 2022
$444k
NCI NIH HHS R01 CA249909NHLBI NIH HHS R01 HL171992NHLBI NIH HHS R33 HL161816NIBIB NIH HHS P41 EB013598NIDDK NIH HHS R21 DK130002NIH HHS S10 OD025077
6 · The paper itself

Abstract

Fitting rate constants to Hyperpolarized [1-

Indexed as

BrainMagnetic Resonance ImagingAlgorithmsCarbon IsotopesComputer SimulationHumansImage Processing, Computer-AssistedLactic AcidNeural Networks, ComputerPhantoms, ImagingPyruvic AcidSignal-To-Noise RatioCarbon IsotopesLactic AcidPyruvic Acid(13)CConvolutional neural networksHyperpolarizedK(PL)Parameter estimationU-Net

Identifiers

PMID39818019
PMCPMC11807744

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.