Evidence map›Paper›PMID 39817941›Full record

ArticleSocial science & medicine (1982)2025

Association between homelessness and PrEP uptake among men who have sex with men: Results from the American Men's Internet Survey, 2017-2021.

Yuanqi Mi, John Mark Wiginton, Sarah M Murray, Iaah Lucas, Mariah Valentine-Graves, Lorraine T Dean, Tiara C Willie, Kalai Willis, Travis Sanchez, Stefan Baral and 1 more

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In one paragraph

Article in Social science & medicine (1982), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuanqi MiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: ymi3@jhu.edu.
John Mark WigintonDepartment of Medicine, Division of Infectious Diseases and Global Public Health, University of California-San Diego, La Jolla, CA, USA.
Sarah M MurrayDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Iaah LucasDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Mariah Valentine-GravesDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Lorraine T DeanDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Tiara C WillieDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Kalai WillisDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Travis SanchezDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Stefan BaralDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Amrita RaoDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
Integrating the Visualization and Use of Stigma Data to Maximize the Impact of the Ending the HIV Epidemic InitiativeR01MH132150 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Stefan David Baral · 2022 to 2026
$5.1M
Characterizing the role of social, behavioral, and economic stigmas as determinants of HIV and mental health across the USR01NR020437 · NINR · JOHNS HOPKINS UNIVERSITY · PI BARAL, STEFAN DAVID · 2021 to 2025
$3.9M
The Johns Hopkins and Emory University AIDS Research Center – Center for HIV and Mental Health Stigma Elimination Strategies (CHIMES) P30MH136919 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Stefan David Baral, Patrick Sean Sullivan · 2024 to 2026
$2.9M
Program and implementation context of a housing support initiative to address homelessness and improve HIV service uptake among youth in the United StatesK01MD020002 · NIMHD · JOHNS HOPKINS UNIVERSITY · PI Amrita Rao · 2024 to 2026
$381k
NIAID NIH HHS P30 AI094189NIDA NIH HHS T32 DA023356NIMHD NIH HHS K01 MD020002NIMH NIH HHS P30 MH136919NIMH NIH HHS R01 MH132150NINR NIH HHS R01 NR020437
6 · The paper itself

Abstract

backgroundGay, bisexual, and other men who have sex with men (GBMSM) are disproportionately affected by housing insecurity across the US. This study examined the association between homelessness and uptake of pre-exposure prophylaxis (PrEP) for HIV prevention among GBMSM in the United States and investigated the modifying effect of injection drug use.

methods47,750 cisgender GBMSM who participated in the American Men's Internet Survey from 2017 to 2021 and who self-reported not living with HIV were included in this secondary, cross-sectional analysis. Homelessness was defined as living on the street, a shelter, a Single Room Occupancy hotel, or a car in the past 12 months. Associations between sociodemographic characteristics and homelessness were tested using chi-squared tests. Weighted univariable and multivariable Poisson regression models with robust variance estimation assessed associations between homelessness and PrEP uptake; weights were constructed based on race/ethnicity and region.

results8304(17.4%) participants reported PrEP uptake in the last 12 months. Those experiencing homelessness were more likely to be younger, Black, uninsured, living in the US South, and report lifetime injection drug use. Homelessness was independently negatively associated with PrEP uptake (aPR = 0.85; 95%CI: 0.75, 0.95). Homelessness was negatively associated with PrEP uptake in those not reporting injection drug use (aPR = 0.77; 95%CI: 0.67, 0.90). However, homelessness was not associated with PrEP uptake in those reporting injection drug use.

conclusionsHomelessness was associated with lower PrEP uptake among GBMSM. Outreach and peer-based interventions tailored specifically to homeless GBMSM are needed given the disproportionate need. Future research on the impact of macro-level systems of inequality and individuals with marginalized identities are needed to unpack intersectional vulnerabilities.

Indexed as

Homosexuality, MaleIll-Housed PersonsPre-Exposure ProphylaxisSexual and Gender MinoritiesAdultCross-Sectional StudiesHIV InfectionsHumansInternetMaleMiddle AgedSurveys and QuestionnairesUnited StatesEpidemiologyHIVHomelessnessMSMPrEPPrevention

Identifiers

PMID39817941
PMCPMC11892117

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.