Evidence map›Paper›PMID 39817789›Full record

ArticleMicrobiology spectrum2025

Macrolide resistance due to

David C Alexander, Tayah Farquhar, Joshua M E Adams, Danae M Suchan, Sean D Workman, Richard J Wallace, Barbara A Brown-Elliott, Omar M El-Halfawy, Andrew D S Cameron

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Molecular Mechanisms Underlying Antimicrobial Resistance in Mycobacteria.International journal of molecular sciences · 2026
    Review
  2. CutaneousMicroorganisms · 2026
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David C AlexanderDepartment of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0003-3509-445X
Tayah FarquharInstitute for Microbial Systems and Society, Faculty of Science, University of Regina, Regina, Saskatchewan, Canada.
Joshua M E AdamsDepartment of Chemistry and Biochemistry, Faculty of Science, University of Regina, Regina, Saskatchewan, Canada.
Danae M SuchanInstitute for Microbial Systems and Society, Faculty of Science, University of Regina, Regina, Saskatchewan, Canada.ORCID 0000-0001-8961-652X
Sean D WorkmanInstitute for Microbial Systems and Society, Faculty of Science, University of Regina, Regina, Saskatchewan, Canada.ORCID 0000-0001-8807-4466
Richard J WallaceMycobacteria/Nocardia Laboratory, The University of Texas at Tyler Health Science Center, UT Tyler School of Medicine, Tyler, Texas, USA.
Barbara A Brown-ElliottMycobacteria/Nocardia Laboratory, The University of Texas at Tyler Health Science Center, UT Tyler School of Medicine, Tyler, Texas, USA.ORCID 0000-0002-3091-1169
Omar M El-HalfawyDepartment of Chemistry and Biochemistry, Faculty of Science, University of Regina, Regina, Saskatchewan, Canada.ORCID 0000-0003-2829-5851
Andrew D S CameronInstitute for Microbial Systems and Society, Faculty of Science, University of Regina, Regina, Saskatchewan, Canada.ORCID 0000-0003-1560-8572

Funding

Canadian Government | Canadian Institutes of Health Research (CIHR) Strategic Master's AwardCanadian Government | Natural Sciences and Engineering Research Council of Canada (NSERC) RGPIN-2019-07135Canadian Government | Natural Sciences and Engineering Research Council of Canada (NSERC) RGPIN-2022-04239
6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a global threat. The identification and characterization of novel resistance genes is integral to AMR surveillance. The IMPORTANCE: Macrolide antibiotics are often the only oral treatment option for infections with rapidly growing mycobacteria such as

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDrug Resistance, BacterialMacrolidesMethyltransferasesMycobacterium chelonaeAzithromycinClarithromycinEscherichia coliMicrobial Sensitivity TestsMycobacterium abscessusPlasmidsAnti-Bacterial AgentsAzithromycinBacterial ProteinsClarithromycinMacrolidesMethyltransferasesantibiotic resistancemolecular biologyMycobacterium

Identifiers

PMID39817789
PMCPMC11878018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.