Evidence map›Paper›PMID 39817757›Full record

ArticleJournal of clinical microbiology2025

Evaluating the clinical utility of

Varshini Gali, Rakan Al-Ghanamah, Katie Finnigan, Or Kalchiem-Dekel, Mini Kamboj, Tobias M Hohl, N Esther Babady, Genovefa A Papanicolaou, Yeon Joo Lee

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Varshini Gali *Department of Medicine, Weill Cornell Medical College, New York, New York, USA.ORCID 0000-0003-2178-8813
Rakan Al-Ghanamah *Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Katie FinniganInfectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Or Kalchiem-DekelDepartment of Medicine, Weill Cornell Medical College, New York, New York, USA.
Mini KambojDepartment of Medicine, Weill Cornell Medical College, New York, New York, USA.
Tobias M HohlDepartment of Medicine, Weill Cornell Medical College, New York, New York, USA.ORCID 0000-0002-9097-5412
N Esther BabadyInfectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0003-4399-1249
Genovefa A PapanicolaouDepartment of Medicine, Weill Cornell Medical College, New York, New York, USA.
Yeon Joo LeeDepartment of Medicine, Weill Cornell Medical College, New York, New York, USA.ORCID 0000-0002-2997-0217

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Invasive pulmonary infections are a significant cause of morbidity and mortality in patients with hematological malignancies and hematopoietic stem cell transplantation (HCT) recipients. A delay in identifying a causative agent may result in late initiation of appropriate treatment and adverse clinical outcomes. We examine the diagnostic utility of PCR-based assays in evaluating invasive pulmonary infections from bronchoalveolar lavage (BAL). Patients with hematological malignancies and HCT recipients who underwent bronchoscopy with BAL from January 2020 to January 2024 for unexplained pulmonary infiltrates and had ≥1 PCR targeting

Indexed as

AspergillusBronchoalveolar Lavage FluidHematologic NeoplasmsInvasive Pulmonary AspergillosisMucoralesNocardiaNocardia InfectionsPolymerase Chain ReactionAdultAgedFemaleHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedMucormycosisAspergillus PCRbronchioalveolar lavagehematologic malignancieshematopoietic stem cell transplantinvasive pulmonary aspergillosisinvasive pulmonary infectionsMucorales PCRNocardia PCRpulmonary mucormycosispulmonary nocardiosis

Identifiers

PMID39817757
PMCPMC11837534

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.